Apple Pharmaceuticals
Apple Pharmaceuticals
Andheri West, Mumbai, Maharashtra
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HIV Medicine

Our product range includes a wide range of velasof, velpanat, lamivir tablets, viraday (tenofovir, emtricitabine, efavirenz) tablets, tenofovir and lamivudine tablets and empetus (ritonavir).

Velasof

Velasof
  • Velasof
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Approx. Price: Rs 20,000 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Strength/Dose (in mg or ml)Velpatasvir 100Mg Sofosbuvir 400Mg
Pack Size28 tablets/bottle
Product TypeFinish Product
BrandHetro

Brand name: Velasof

Active Ingeridents: Velpatasvir Sofosbuvir

Company Name: Hetro

Package: 28 tablets/bottle

Strength :Velpatasvir 100Mg Sofosbuvir 400Mg

 

Indication:

Velasof is an combination of velpatasvir 100mg+ Sofosbuvir 400mg. Velasof is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing the viral NS5A inhibitor velpatasvir and sofosbuvir,a nucleotide inhibitor of the viral RNA polymerase. It is the first treatment, that works for all genotypic, and is taken entirely by mouth. A single tablet regimen is used for adults with genotype 1-6 chronic hepatitis C virus (HCV) infection with pangenotypic activity.

Dosage and Administration:

Take Velasof exactly as your healthcare provider tells you to.

·         Patients without cirrhosis or with compensated cirrhosis (Child-Pugh A): Velasof for 12 weeks.

·         Patients with decompensated cirrhosis (Child-Pugh B or C): Velasof

·         plus weight-based ribavirin with food for 12 weeks

·         Weight-based ribavirin dose.

·         Less than 75 kg: 1000 mg/day PO divided BID

·         ≥75 kg: 1200 mg/day PO divided BID

·         Ribavirin starting dose and on-treatment dosage should be modified based on hemoglobin and creatinine clearance

·         Dose modification:Severe renal impairment (eGFR less than 30mL/min/1.73 m²) or ESRD: No dosage recommendation can be give owing to higher exposures (up to 20-fold) of the predominant sofosbuvir metabolite

 

Side effects:

The most common adverse reactions with velpatasvir were headache and fatigue and when used with RBV in decompensated cirrhotics were fatigue, anemia, nausea, headache, insomnia, and diarrhea.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

storage:

Velasof Store below 30°C (86 ºF)

 

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Velpanat

Velpanat
  • Velpanat
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Approx. Price: Rs 20,000 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size28's Tablets
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)velpatasvir 100mg & sofosbuvir 400mg
UsageClinical, Hospital, Personal

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Lamivir Tablets

Lamivir Tablets
  • Lamivir Tablets
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Approx. Price: Rs 110 / Strip

Product Details:

Minimum Order Quantity1 Strip
Packaging Size10 Tablets Per Strip
Packaging TypeStrip
UsageClinical, Hospital

Product Description Item Code: 66968801We are counted among the leading manufacturer, trader, exporter and supplier of best quality Lamivir Tablets that is widely used for the treatment of chronic hepatitis B. Owing to its effectiveness; our offered tablets are highly demanded in the market. At our premises, our offered tablets are processed using quality assured chemical compounds that are sourced from the reliable vendors of the market. Additionally, these tablets can get by our clients from us at reasonable prices.
Features:
  • Accurate composition
  • Highly effective
  • No side effect
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Viraday (Tenofovir, Emtricitabine, Efavirenz) Tablets

Viraday (Tenofovir, Emtricitabine, Efavirenz) Tablets
  • Viraday (Tenofovir, Emtricitabine, Efavirenz) Tablets
Approx. Rs 3,500 / Bottle
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Tenofovir and Lamivudine Tablets

Tenofovir and Lamivudine Tablets
  • Tenofovir and Lamivudine Tablets
Approx. Rs 1,500 / Bottle
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Tenofovir and Lamivudine Tablets

Tenofovir and Lamivudine Tablets
  • Tenofovir and Lamivudine Tablets
Approx. Rs 1,500 / bottle
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Empetus (Ritonavir)

Empetus (Ritonavir)
  • Empetus (Ritonavir)
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Approx. Price: Rs 970 / Bottle
Item Code: 83994873

Empetus (Ritonavir)

Brand name: Empetus

Active Ingeridents(Generic Name) : Ritonavir

Company Name: Emcure

Package:30 Tablets/Bottle

Strength : 100mg

Indication:

Empetus (Ritonavir) is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy . Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C.

Mechanism of action:

Empetus (Ritonavir) was originally developed as an inhibitor of HIV protease. It is one of the most complex inhibitors. It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, Empetus (Ritonavir) is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). The drug's molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors. This discovery, which has drastically reduced the adverse effects and improved the efficacy of protease inhibitors and HAART, was first communicated in an article published in the journal AIDS in 1997 by researchers at the University of Liverpool. This effect does come with a price: it also affects the efficacy of numerous other medications, making it difficult to know how to administer them concurrently.

Dosage and Administration:

Use Empetus (Ritonavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· Take Empetus (Ritonavir) by mouth with meals.

· Swallow Empetus (Ritonavir) whole. Do not break, crush, or chew before swallowing.

· Continue to take Empetus (Ritonavir) even if you feel well. Do not miss any doses.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations, especially around the mouth, fingers, and toes; diarrhea; headache; loss of appetite; mild stomach pain; nausea; taste changes; tiredness; vomiting; weakness.

Precaution:

Before taking Empetus (Ritonavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart problems (coronary artery disease, heart attack), hemophilia, high cholesterol/triglycerides, gout/high uric acid in the blood, liver problems (such as hepatitis B, hepatitis C), pancreatitis

 

Store:

Store Empetus (Ritonavir) in the original container at room temperature up to 86 degrees F (30 degrees C). If stored outside of the original container, throw away any part not used after 2 weeks. Storage at temperatures up to 122 degrees F (50 degrees C) is permitted for up to 7 days. Store away from heat, moisture, and light.

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  • Minimum Order Quantity: 1 Bottle
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Emletra (Lopinavir /Ritonavir) Medicines

Emletra (Lopinavir /Ritonavir) Medicines
  • Emletra (Lopinavir /Ritonavir) Medicines
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Approx. Price: Rs 2,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size60 tablets
Dose/Strength (ex. 1 mg or 1 ml)Lopinavir 200mg+ Ritonavir 50mg

Item Code: 85672320

Emletra (Lopinavir /Ritonavir)

Brand name: Emletra

Active Ingeridents(Generic Name) : Lopinavir / Ritonavir

Company Name: Emcure

Package : 60 tablets

Strength : Lopinavir 200mg+ Ritonavir 50mg

Indication:

Treating HIV infection. It is used along with other medicines for HIV. Emletra (Lopinavir /Ritonavir) is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

 

Mechanism of action:

Lopinavir:

Lopinavir inhibits the HIV viral protease enzyme. This prevents cleavage of the gag-pol polyprotein and, therefore, improper viral assembly results. This subsequently results in non-infectious, immature viral particles

Ritonavir :

Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

Dosage and Administration:

Use Emletra (Lopinavir /Ritonavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Emletra (Lopinavir /Ritonavir) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Emletra (Lopinavir /Ritonavir) refilled.

· Take Emletra (Lopinavir /Ritonavir) by mouth with or without food.

· Swallow Emletra (Lopinavir /Ritonavir) whole. Do not break, crush, or chew before swallowing.

· Emletra (Lopinavir /Ritonavir) must be taken with other HIV medicines to be effective.

· If you are also taking didanosine, you may take it at the same time as Emletra (Lopinavir /Ritonavir) without food.

· Taking Emletra (Lopinavir /Ritonavir) at the same time each day will help you remember to take it.

Ask your health care provider any questions you may have about how to use Emletra (Lopinavir /Ritonavir).

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; headache; muscle or joint pain; nausea; stomach pain; tiredness; vomiting; weakness.

Precaution:

Before taking this product, tell your doctor or pharmacist if you are allergic to either lopinavir or ritonavir; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details

 

Store:

Store Emletra (Lopinavir /Ritonavir) at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light.

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Efavir (Efavirenz) Medicines

Efavir (Efavirenz) Medicines
  • Efavir (Efavirenz) Medicines
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Approx. Price: Rs 1,890 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablets/Bottle
Dose/Strength (ex. 1 mg or 1 ml) 600mg

Item Code: 83994383

Efavir (Efavirenz)

Brand name: Efavir

Active Ingeridents(Generic Name) : Efavirenz

Company Name: Cipla

Package: 30 Tablets/Bottle

Strength : 600mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Efavir (Efavirenz) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Mechanism of action:

Efavir (Efavirenz) falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.

Efavir (Efavirenz) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

Dosage and Administration:

Use Efavir (Efavirenz) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Efavir (Efavirenz) by mouth on an empty stomach. Taking Efavir (Efavirenz) with food, especially with a high-fat meal, may lead to increased blood levels of Efavir (Efavirenz). This may increase your risk of side effects.

· Take Efavir (Efavirenz) with a full glass of water (8 oz [240 mL]).

· Swallow Efavir (Efavirenz) whole. Do not break, crush, or chew before swallowing. If you cannot swallow Efavir (Efavirenz) whole, tell your doctor.

· Do NOT take more than the recommended dose, change your dose, or stop taking Efavir (Efavirenz) without checking with your doctor.

· Take Efavir (Efavirenz) at the same time every day, preferably at bedtime unless otherwise directed by your doctor.

· Continue to use Efavir (Efavirenz) even if you feel well. Do not miss any doses.

 

Side effects:

Dizziness, trouble sleeping, drowsiness, unusual dreams, and trouble concentrating may frequently occur. These side effects may begin 1-2 days after starting this medication and usually go away in 2-4 weeks. They are also reduced by taking Efavir (Efavirenz) on an empty stomach at bedtime. Avoid alcohol and street drugs while taking Efavir (Efavirenz). They may worsen these side effects. Tiredness, headache, nausea, vomiting, and diarrhea may also occur.

Precaution:

Before taking Efavir (Efavirenz), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Store:

Store Efavir (Efavirenz) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container away from heat, moisture, and light.

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Duovir (Zidovudine /Lamivudine) Medicines

Duovir (Zidovudine /Lamivudine) Medicines
  • Duovir (Zidovudine /Lamivudine) Medicines
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Approx. Price: Rs 1,020 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size60 Tablets /Bottle
Dose/Strength (ex. 1 mg or 1 ml)Zidovudine 300mg + Lamivudine 150mg

Item Code: 85671748

Duovir (Zidovudine /Lamivudine)

Brand name: Duovir

Active Ingeridents(Generic Name) : Zidovudine /Lamivudine

Company Name: Cipla

Package :60 Tablets /Bottle

Strength : Zidovudine 300mg + Lamivudine 150mg

Indication:

Duovir (Zidovudine /Lamivudine) are antiviral medications that prevent human immunodeficiency virus (HIV) cells from multiplying in your body.

Duovir (Zidovudine /Lamivudine) is a combination medicine used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AID.

 

 

Mechanism of action:

Zidovudine:

Zidovudine, a structural analog of thymidine, is a prodrug that must be phosphorylated to its active 5′-triphosphate metabolite, zidovudine triphosphate (ZDV-TP). It inhibits the activity of HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleotide analogue. It competes with the natural substrate dGTP and incorporates itself into viral DNA. It is also a weak inhibitor of cellular DNA polymerase α and γ.

Lamivudine:

Lamivudine is a synthetic nucleoside analogue and is phosphorylated intracellularly to its active 5'-triphosphate metabolite, lamivudine triphosphate (L-TP). This nucleoside analogue is incorporated into viral DNA by HIV reverse transcriptase and HBV polymerase, resulting in DNA chain termination.

Dosage and Administration:

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Duovir (Zidovudine /Lamivudine) can be taken with or without food.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Side effects:

Headache, tiredness, loss of appetite, nausea, vomiting, diarrhea, trouble sleeping, dizziness, or stuffy nose may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Duovir (Zidovudine /Lamivudine), tell your doctor or pharmacist if you are allergic to either drug; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems (such as hepatitis B or C, cirrhosis), disease of the pancreas (pancreatitis), alcohol use, low red/white blood cell counts.

Store: Duovir (Zidovudine /Lamivudine) room temperature away from moisture and heat or cold. Do not freeze.

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Daruvir (Darunavir) Medicines

Daruvir (Darunavir) Medicines
  • Daruvir (Darunavir) Medicines
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Approx. Price: Rs 4,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size60 Tabs/Bottle
Dose/Strength (ex. 1 mg or 1 ml)Strength : 300mg

Item Code: 83994299

Daruvir (Darunavir)

Brand name: Daruvir 

Active Ingeridents(Generic Name) : Darunavir

Company Name: Cipla

Package:60 Tabs/Bottle

Strength : 300mg

Indication:

Treating HIV infection in certain patients along with other antiretroviral medicines. Daruvir (Darunavir) must always be taken along with another medicine called ritonavir. Daruvir (Darunavir) is an HIV protease inhibitor. It works by blocking the growth of HIV.

Mechanism of action:

Daruvir (Darunavir) is a HIV protease inhibitor which prevents HIV replication by binding to the enzyme's active site, thereby preventing the dimerization and the catalytic activity of the HIV-1 protease. Daruvir (Darunavir) selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virus particles. Structual analyses suggests that the close contact that Daruvir (Darunavir) has with the main chains of the protease active site amino acids (Asp-29 and Asp-30) is an important contributing factor to its potency and wide spectrum of activity against multi-protease inhibitor resistant HIV-1 variants. Daruvir (Darunavir) can also adapt to the changing shape of a protease enzyme because of its molecular flexibility. Daruvir (Darunavir) is known to bind to two distinct sites on the enzyme: the active site cavity and the surface of one of the flexible flaps in the protease dimer.

 

Dosage and Administration:

Use Daruvir (Darunavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· Take Daruvir (Darunavir) by mouth with food. Ritonavir should be taken at the same time as Daruvir (Darunavir).

· Swallow Daruvir (Darunavir) whole with a drink, such as water or milk. Do not break, crush, or chew before swallowing. If you are unable to swallow Daruvir (Darunavir) whole, contact your doctor. Daruvir (Darunavir) may not be right for you.

· If you also take didanosine, do not take it within 1 hour before or 2 hours after taking Daruvir (Darunavir). Check with your doctor if you have questions.

· Taking Daruvir (Darunavir) at the same time(s) each day will help you remember to take it.

· Continue to take Daruvir (Darunavir) even if you feel well. Do not miss any doses.

 

Side effects:

Since Daruvir (Darunavir) is always taken with other HIV medications, it may be difficult to tell whether Daruvir (Darunavir) is causing certain side effects. However, Daruvir (Darunavir) is known to cause diarrhea, nausea, vomiting, stomach pain, and headache. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Daruvir (Darunavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Since Daruvir (Darunavir) must be taken with ritonavir, tell your doctor if you are allergic to ritonavir. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store:

Store Daruvir (Darunavir) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light.

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Daruvir (Darunavir) Medicines

Daruvir (Darunavir) Medicines
  • Daruvir (Darunavir) Medicines
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Approx. Price: Rs 10,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size60 Tabs/Bottle
Dose/Strength (ex. 1 mg or 1 ml)Strength : 600mg

Item Code: 83994255

Daruvir (Darunavir)

Brand name: Daruvir 

Active Ingeridents(Generic Name) : Darunavir

Company Name: Cipla

Package:60 Tabs/Bottle

Strength : 600mg

Indication:

Treating HIV infection in certain patients along with other antiretroviral medicines. Daruvir (Darunavir) must always be taken along with another medicine called ritonavir. Daruvir (Darunavir) is an HIV protease inhibitor. It works by blocking the growth of HIV.

Mechanism of action:

Daruvir (Darunavir) is a HIV protease inhibitor which prevents HIV replication by binding to the enzyme's active site, thereby preventing the dimerization and the catalytic activity of the HIV-1 protease. Daruvir (Darunavir) selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virus particles. Structual analyses suggests that the close contact that Daruvir (Darunavir) has with the main chains of the protease active site amino acids (Asp-29 and Asp-30) is an important contributing factor to its potency and wide spectrum of activity against multi-protease inhibitor resistant HIV-1 variants. Daruvir (Darunavir) can also adapt to the changing shape of a protease enzyme because of its molecular flexibility. Daruvir (Darunavir) is known to bind to two distinct sites on the enzyme: the active site cavity and the surface of one of the flexible flaps in the protease dimer.

 

Dosage and Administration:

Use Daruvir (Darunavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Daruvir (Darunavir) by mouth with food. Ritonavir should be taken at the same time as Daruvir (Darunavir).

· Swallow Daruvir (Darunavir) whole with a drink, such as water or milk. Do not break, crush, or chew before swallowing. If you are unable to swallow Daruvir (Darunavir) whole, contact your doctor. Daruvir (Darunavir) may not be right for you.

· If you also take didanosine, do not take it within 1 hour before or 2 hours after taking Daruvir (Darunavir). Check with your doctor if you have questions.

· Taking Daruvir (Darunavir) at the same time(s) each day will help you remember to take it.

· Continue to take Daruvir (Darunavir) even if you feel well. Do not miss any doses.

 

Side effects:

Since Daruvir (Darunavir) is always taken with other HIV medications, it may be difficult to tell whether Daruvir (Darunavir) is causing certain side effects. However, Daruvir (Darunavir) is known to cause diarrhea, nausea, vomiting, stomach pain, and headache. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Daruvir (Darunavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Since Daruvir (Darunavir) must be taken with ritonavir, tell your doctor if you are allergic to ritonavir. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store:

Store Daruvir (Darunavir) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light.

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Atazor-R (Atazanavir / Ritonavir )

Atazor-R (Atazanavir / Ritonavir )
  • Atazor-R (Atazanavir / Ritonavir )
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Approx. Price: Rs 2,800 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size 30 Tablets/Bottle
Dose/Strength (ex. 1 mg or 1 ml)Atazanavir 300mg + Ritonavir 100mg

Item Code: 85673776

 

Atazor-R (Atazanavir / Ritonavir )

Brand name: Atazor-R 

Active Ingeridents(Generic Name) : Atazanavir / Ritonavir

Company Name: Emcure

Package : 30 Tablets/Bottle

Strength : Atazanavir 300mg + Ritonavir 100mg

Indication:

Treating HIV infection. It is used along with other medicines for HIV. Atazor-R (Atazanavir / Ritonavir )is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

 

 

Mechanism of action:

Atazanavir:

Atazanavir selectively inhibits the virus-specific processing of viral Gag and Gag-Pol polyproteins in HIV-1 infected cells by binding to the active site of HIV-1 protease, thus preventing the formation of mature virions. Atazanavir is not active against HIV-2.

Ritonavir :

Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

 

Dosage and Administration:

· An extra patient leaflet is available with Atazor-R (Atazanavir / Ritonavir ). Talk to your pharmacist if you have questions about this information.

· Take Atazor-R (Atazanavir / Ritonavir )by mouth with or without food.

· Continue to take Atazor-R (Atazanavir / Ritonavir )even if you feel well. Do not miss any doses.

· Taking Atazor-R (Atazanavir / Ritonavir )at the same time each day will help you remember to take it.

· If you miss a dose of Atazor-R (Atazanavir / Ritonavir ), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

Below are the common side effects that may occur when using Atazor-R (Atazanavir / Ritonavir )Tablet. Please consult your doctor if you observe any of these side effects even in mild form.

· Abdominal pain , Accumulation of body fat, Anxiety, Asthma

 

Precaution:

Take the following precautions or be careful about the following while consuming Atazor-R (Atazanavir / Ritonavir ) Tablet:

· Children , Consult a doctor if you have haemophilia or pancreatitis, Kidney problems

 

store: Atazor-R (Atazanavir / Ritonavir )room temperature away from moisture and heat or cold. Do not freeze.

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Tenvir EM Tablet

Tenvir EM Tablet
  • Tenvir EM Tablet
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Approx. Price: Rs 950 / Bottle
Item Code: 67916625

Tenvir-EM Tablet

Packing : Pack of 30 Tablets

Uses:
  • Tenvir EM Tablet is used in combination with other antiretroviral medications for the treatment of HIV-1 infection in adults
  • It is also used to treat chronic hepatitis B infection
  • It may also be used for other conditions as determined by your doctor
  • Tenvir–EM is an antiviral reverse transcriptase inhibitor
  • It works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply
  • It works to treat HBV infection by reducing the amount of HBV in the body by blocking the ability of the virus to multiply and infect new liver cells
  • Tenvir–EM is not a cure for HIV or AIDS
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Terbinafine Tablets

Terbinafine Tablets
  • Terbinafine Tablets
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Approx. Price: Rs 15 / Box
Item Code: 65369482We have carved a niche in offering a supreme quality Terbinafine Tablets which is an acyclic nucleoside phosphonate diester analog o monophosphate. Offered Tenvir-em tablet is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults. our provided Tenvir-em tablet is formulated by vendor’s medical experts using quality ingredients in compliance with the standards of medical industry.
Features:
  • Highly effective
  • No side effects
  • Available in various packaging option

Side effects:
  • Headache
  • Nausea
  • Diarrhea
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Lamivir HBV (Lamivudine)

Lamivir HBV (Lamivudine)
  • Lamivir HBV (Lamivudine)
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Approx. Price: Rs 108 / Piece

Product Details:

Minimum Order Quantity1 Piece
Packaging Size10 Tablets per piece
Dose/Strength (ex. 1 mg or 1 ml)100mg

Item Code: 83994504

LamivirHBV (Lamivudine)

Brand name: LamivirHBV

Active Ingeridents(Generic Name) : Lamivudine

Company Name: Cipla

Package:10 Tablets

Strength : 100mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. LamivirHBV (Lamivudine) belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.

Mechanism of action:

LamivirHBV (Lamivudine) is an analogue of cytidine. It can inhibit both types of HIV reverse transcriptase and also the reverse transcriptase of hepatitis B virus. It is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

LamivirHBV (Lamivudine) is administered orally, and it is rapidly absorbed with a bio-availability of over 80%. Some research suggests that LamivirHBV (Lamivudine) can cross the blood–brain barrier. LamivirHBV (Lamivudine) is often given in combination with zidovudine, with which it is highly synergistic. LamivirHBV (Lamivudine) treatment has been shown to restore zidovudine sensitivity of previously resistant HIV. LamivirHBV (Lamivudine) showed no evidence of carcinogenicity or mutagenicity in in vivo studies in mice and rats at doses from 10 to 58 times those used in humans.

Dosage and Administration:

Use LamivirHBV (Lamivudine) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take LamivirHBV (Lamivudine) by mouth with or without food.

· Continue to take LamivirHBV (Lamivudine) even if you feel well. Do not miss any doses.

· Taking LamivirHBV (Lamivudine) at the same time each day will help you remember to take it.

· If you miss a dose of LamivirHBV (Lamivudine), take it as soon as possible. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

See also Warning section.

Headache, dizziness, nausea, diarrhea, or trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Precaution:

Before taking LamivirHBV (Lamivudine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: pancreatitis, kidney problems, liver problems (such as hepatitis B or C, cirrhosis), alcohol use.

Store:

Store LamivirHBV (Lamivudine) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light.

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Tenvir EM Tablet

Tenvir EM Tablet
  • Tenvir EM Tablet
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Approx. Price: Rs 950 / Pack

Product Details:

Minimum Order Quantity1 Pack
Packaging Size30 Tablet
UsageClinical, Hospital, Personal

Tenvir-EM Tablet


Packing : Pack of 30 Tablets

Uses:

Tenvir EM Tablet is used in combination with other antiretroviral medications for the treatment of HIV-1 infection in adults

It is also used to treat chronic hepatitis B infection

It may also be used for other conditions as determined by your doctor

Tenvir–EM is an antiviral reverse transcriptase inhibitor

It works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply

It works to treat HBV infection by reducing the amount of HBV in the body by blocking the ability of the virus to multiply and infect new liver cells

Tenvir–EM is not a cure for HIV or AIDS.

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Daruvir (Darunavir) Medicines

Daruvir (Darunavir) Medicines
  • Daruvir (Darunavir) Medicines
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Approx. Price: Rs 10,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size60 Tablets Per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)600mg
UsageClinical, Hospital, Personal

Daruvir (Darunavir)

Brand name: Daruvir

Active Ingeridents(Generic Name) : Darunavir

Company Name: Cipla

Package:60 Tabs/Bottle

Strength : 600mg

Indication:

Treating HIV infection in certain patients along with other antiretroviral medicines. Daruvir (Darunavir) must always be taken along with another medicine called ritonavir. Daruvir (Darunavir) is an HIV protease inhibitor. It works by blocking the growth of HIV.

Mechanism of action:

Daruvir (Darunavir) is a HIV protease inhibitor which prevents HIV replication by binding to the enzyme's active site, thereby preventing the dimerization and the catalytic activity of the HIV-1 protease. Daruvir (Darunavir) selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virus particles. Structual analyses suggests that the close contact that Daruvir (Darunavir) has with the main chains of the protease active site amino acids (Asp-29 and Asp-30) is an important contributing factor to its potency and wide spectrum of activity against multi-protease inhibitor resistant HIV-1 variants. Daruvir (Darunavir) can also adapt to the changing shape of a protease enzyme because of its molecular flexibility. Daruvir (Darunavir) is known to bind to two distinct sites on the enzyme: the active site cavity and the surface of one of the flexible flaps in the protease dimer.

Dosage and Administration:

Use Daruvir (Darunavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Daruvir (Darunavir) by mouth with food. Ritonavir should be taken at the same time as Daruvir (Darunavir).

· Swallow Daruvir (Darunavir) whole with a drink, such as water or milk. Do not break, crush, or chew before swallowing. If you are unable to swallow Daruvir (Darunavir) whole, contact your doctor. Daruvir (Darunavir) may not be right for you.

· If you also take didanosine, do not take it within 1 hour before or 2 hours after taking Daruvir (Darunavir). Check with your doctor if you have questions.

· Taking Daruvir (Darunavir) at the same time(s) each day will help you remember to take it.

· Continue to take Daruvir (Darunavir) even if you feel well. Do not miss any doses.

Side effects:

Since Daruvir (Darunavir) is always taken with other HIV medications, it may be difficult to tell whether Daruvir (Darunavir) is causing certain side effects. However, Daruvir (Darunavir) is known to cause diarrhea, nausea, vomiting, stomach pain, and headache. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Daruvir (Darunavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Since Daruvir (Darunavir) must be taken with ritonavir, tell your doctor if you are allergic to ritonavir. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store:

Store Daruvir (Darunavir) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light.

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Tenvir (Tenofovir ) Medicines

Tenvir (Tenofovir ) Medicines
  • Tenvir (Tenofovir ) Medicines
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Approx. Price: Rs 1,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablet
Dose/Strength (ex. 1 mg or 1 ml)300mg
UsageClinical, Hospital, Personal

Tenvir (Tenofovir )

Brand name: Tenvir

Active Ingeridents(Generic Name) : Tenofovir disoproxil Fumerate

Company Name: Cipla

Package:30 Tablets

Strength : 300mg

Indication:

Tenvir (Tenofovir ) is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

Mechanism of action:

Tenvir (Tenofovir ) is a defective adenosine nucleotide that selectively inhibits the action of reverse transcriptase, while only weakly interfering with mammalian DNA polymerases α, β, and mitochondrial DNA polymerase γ. Tenvir (Tenofovir ) prevents the formation of the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation. A phosphodiester bond cannot be formed because the Tenvir (Tenofovir ) molecule lacks an —OH group on the 3′ carbon of its deoxyribose sugar. Once incorporated into a growing DNA strand, Tenvir (Tenofovir ) causes premature termination of DNA transcription. The drug is classified as a nucleotide analogue reverse transcriptase inhibitor (NtRTI). Reverse transcriptase is a crucial viral enzyme in retroviruses such as human immunodeficiency virus (HIV) and in hepatitis B virus infections.

Dosage and Administration:

Use Tenvir (Tenofovir ) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· An extra patient leaflet is available with Tenvir (Tenofovir ). Talk to your pharmacist if you have questions about this information.

· Take Tenvir (Tenofovir ) by mouth with or without food.

· Continue to take Tenvir (Tenofovir ) even if you feel well. Do not miss any doses.

· Taking Tenvir (Tenofovir ) at the same time each day will help you remember to take it.

· Do not suddenly stop taking Tenvir (Tenofovir ) without checking with your doctor. This may cause the virus to become less sensitive to this or other medicines. If you have hepatitis B, your condition could become worse if you suddenly stop taking Tenvir (Tenofovir ).

· If you miss a dose of Tenvir (Tenofovir ), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness; gas; headache; indigestion; loss of appetite; nausea; runny or stuffy nose; sweating; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Precaution:

Before taking Tenvir (Tenofovir ), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Store: Store Tenvir (Tenofovir ) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light.

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Tenofovir Tablet

Tenofovir Tablet
  • Tenofovir Tablet
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Approx. Price: Rs 785 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablet
Dose/Strength (ex. 1 mg or 1 ml)300mg
UsageClinical, Hospital, Personal

Tenvir is an antiviral reverse transcriptase inhibitor. It works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply. Each film coated tablet of Tenvir contains 300 mg of Tenofovir disoproxil fumarate which is equivalent to 245 mg of Tenofovir disoproxil.
Tenofovir Disoproxil Fumarate Tablets is used for Treating HIV infection in combination with other medicines. It is also used to treat chronic hepatitis B infection. It may also be used for other conditions as determined by your doctor. Tenvir is an antiviral reverse transcriptase inhibitor. Tenofovir Disoproxil Fumarate works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply. Tenofovir works to treat HBV infection by reducing the amount of HBV in the body by blocking the ability of the virus to multiply and infect new liver cells. Tenvir is not a cure for HIV or AIDS.
Use Tenvir as directed by your doctor. Check the label on the medicine for exact dosing instructions.An extra patient leaflet is available with Tenvir . Talk to your pharmacist if you have questions about this information.Take Tenvir tablets by mouth with or without food.Continue to take Tenvir even if you feel well. Do not miss any doses.Taking Tenvir at the same time each day will help you remember to take it.Do not suddenly stop taking Tenvir Tablets without checking with your doctor. This may cause thevirus to become less sensitive to this or other medicines. Also, some conditions (eg, hepatitis B) could become worse if you suddenly stop taking Tenofovir Disoproxil Fumarate Tablets (Tenvir) .If you miss a dose of Tenvir , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Tenvir .
Storage Instructions for Tenvir TabletsStore Tenvir Tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Do not use Tenvir if the seal over the bottle opening is broken or missing. Keep Tenvir in its original container and keep the container tightly closed. Do not keep medicine that is out of date or that you no longer need. If you throw any medicines away, make sure that children or pets cannot find them. Keep Tenvir out of the reach of children and away from pets.
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Ritomune (Ritonavir) Medicines

Ritomune (Ritonavir) Medicines
  • Ritomune (Ritonavir) Medicines
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Approx. Price: Rs 1,800 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size60 Tablet per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)60mg
UsageClinical, Hospital, Personal

Ritomune (Ritonavir)

Brand name: Ritomune

Active Ingeridents(Generic Name) : Ritonavir

Company Name: Cipla

Package:60 Tablets/Bottle

Strength : 100mg

Indication:

Ritomune (Ritonavir) is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy . Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C.

Mechanism of action:

Ritomune (Ritonavir) was originally developed as an inhibitor of HIV protease. It is one of the most complex inhibitors. It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, Ritomune (Ritonavir) is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). The drug's molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors. This discovery, which has drastically reduced the adverse effects and improved the efficacy of protease inhibitors and HAART, was first communicated in an article published in the journal AIDS in 1997 by researchers at the University of Liverpool. This effect does come with a price: it also affects the efficacy of numerous other medications, making it difficult to know how to administer them concurrently.

Dosage and Administration:

Use Ritomune (Ritonavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Ritomune (Ritonavir) by mouth with meals.

· Swallow Ritomune (Ritonavir) whole. Do not break, crush, or chew before swallowing.

· Continue to take Ritomune (Ritonavir) even if you feel well. Do not miss any doses.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations, especially around the mouth, fingers, and toes; diarrhea; headache; loss of appetite; mild stomach pain; nausea; taste changes; tiredness; vomiting; weakness.

Precaution:

Before taking Ritomune (Ritonavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart problems (coronary artery disease, heart attack), hemophilia, high cholesterol/triglycerides, gout/high uric acid in the blood, liver problems (such as hepatitis B, hepatitis C), pancreatitis

Store:

Store Ritomune (Ritonavir) in the original container at room temperature up to 86 degrees F (30 degrees C). If stored outside of the original container, throw away any part not used after 2 weeks. Storage at temperatures up to 122 degrees F (50 degrees C) is permitted for up to 7 days. Store away from heat, moisture, and light.

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Nevimune (Nevirapine)

Nevimune (Nevirapine)
  • Nevimune (Nevirapine)
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Approx. Price: Rs 850 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size60 Tablet per bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)200mg
UsageClinical, Hospital, Personal

Nevimune (Nevirapine)

Brand name: Nevimune

Active Ingeridents(Generic Name) : Nevirapine

Company Name: Cipla

Package:60 Tablets/Bottle

Strength : 200mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Nevimune (Nevirapine) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Mechanism of action:

Nevimune (Nevirapine) falls in the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs bind allosterically at a distinct site away from the active site termed the NNRTI pocket.

Nevimune (Nevirapine) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

Resistance to Nevimune (Nevirapine) develops rapidly if viral replication is not completely suppressed. The most common mutations observed after Nevimune (Nevirapine) treatment are Y181C and K103N, which are also observed with other NNRTIs. As all NNRTIs bind within the same pocket, viral strains which are resistant to Nevimune (Nevirapine) are usually also resistant to the other NNRTIs, efavirenz and delavirdine. However, second generation NNRTIs like rilpivirine and etravirine are effective in treatment for HIV strains resistant to Nevimune (Nevirapine) and other first generation drugs in that same class.

Dosage and Administration:

Use Nevimune (Nevirapine) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Nevimune (Nevirapine) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Nevimune (Nevirapine) refilled.

· Take Nevimune (Nevirapine) by mouth with or without food.

· Taking Nevimune (Nevirapine) at the same time each day will help you remember to take it.

· Continue to take Nevimune (Nevirapine) even if you feel well. Do not miss any doses.

Side effects:

Tiredness, nausea, vomiting, or diarrhea may occur. Drowsiness may rarely occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Nevimune (Nevirapine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems (such as hepatitis B or C, cirrhosis), kidney dialysis, lactose or galactose intolerance.

Store:

Store Nevimune (Nevirapine) at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light.

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Valten (Tenofovir) Medicines

Valten (Tenofovir) Medicines
  • Valten (Tenofovir) Medicines
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Approx. Price: Rs 2,000 / Piece

Product Details:

Minimum Order Quantity1 Piece
Packaging Size30 Tablets Per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)300mg
UsageClinical, Hospital, Personal

Valten (Tenofovir )

Brand name: Valten

Active Ingeridents(Generic Name) : Tenofovir disoproxil Fumerate

Company Name: Wockhardt

Package:30 Tablets

Strength : 300mg

Indication:

Valten (Tenofovir )is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

Mechanism of action:

Valten (Tenofovir )is a defective adenosine nucleotide that selectively inhibits the action of reverse transcriptase, while only weakly interfering with mammalian DNA polymerases α, β, and mitochondrial DNA polymerase γ. Valten (Tenofovir )prevents the formation of the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation. A phosphodiester bond cannot be formed because the Valten (Tenofovir )molecule lacks an —OH group on the 3′ carbon of its deoxyribose sugar. Once incorporated into a growing DNA strand, Valten (Tenofovir )causes premature termination of DNA transcription. The drug is classified as a nucleotide analogue reverse transcriptase inhibitor (NtRTI). Reverse transcriptase is a crucial viral enzyme in retroviruses such as human immunodeficiency virus (HIV) and in hepatitis B virus infections.

Dosage and Administration:

Use Valten (Tenofovir )as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Valten (Tenofovir )by mouth with or without food.

· Continue to take Valten (Tenofovir )even if you feel well. Do not miss any doses.

· Taking Valten (Tenofovir )at the same time each day will help you remember to take it.

· Do not suddenly stop taking Valten (Tenofovir )without checking with your doctor. This may cause the virus to become less sensitive to this or other medicines. If you have hepatitis B, your condition could become worse if you suddenly stop taking Valten (Tenofovir ).

· If you miss a dose of Valten (Tenofovir ), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness; gas; headache; indigestion; loss of appetite; nausea; runny or stuffy nose; sweating; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Precaution:

Before taking Valten (Tenofovir ), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Store: Store Valten (Tenofovir )at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light.

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Trustiva Tablets

Trustiva Tablets
  • Trustiva Tablets
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Approx. Price: Rs 3,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 TABLET
Dose/Strength (ex. 1 mg or 1 ml)600mg/300mg/200mgTypeTablet
UsageClinical, Hospital

Specifications:

  • Trade Name Trustiva Manufacturer Gen X (Hetero Healthcare Ltd)Unit600mg/300mg/200mgTypeTablet
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Daruvir 300mg

Daruvir 300mg
  • Daruvir 300mg
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Approx. Price: Rs 4,500 / Pack

Product Details:

Minimum Order Quantity1 Pack
Packaging Size60 Tablet per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)600 Mg
UsageClinical, Hospital, Personal

Specifications:

  • Drug name: Darunavir
  • Strength: 600 Mg
  • Packing : Pack of 60 Tablet

 

Uses :

 

  • This medication is an antiviral agent, prescribed for HIV infection with other antiviral agents
  • It is a protease inhibitor and blocks the enzyme activity
  • This medication slows down the spread of virus in the body
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Dolutegravir 50mg

Dolutegravir 50mg
  • Dolutegravir 50mg
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Approx. Price: Rs 10,000 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size28 Tablets per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)50mg
UsageClinical, Hospital, Personal

Dolutegravir 50mg used in the treatment of HIV infections

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A-Bec (Abacavir)

A-Bec (Abacavir)
  • A-Bec (Abacavir)
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Approx. Price: Rs 1,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablets Per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)300mg
UsageClinical, Hospital, Personal

Product Details:

Packaging Size30 TabletPackaging TypeBottleDose/Strength (ex. 1 Mg Or 1 Ml)300 MgUsageHospital/ Personal -Minimum Order Quantity1Item Code: 85288411

A-Bec (Abacavir)

Brand name: A-Bec 

Active Ingeridents(Generic Name) : Abacavir

Company Name: Emcure

Package:30 Tablets/Bottle

Strength : 300mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. A-Bec (Abacavir) belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.

Mechanism of action:

A-Bec (Abacavir) is a carbocyclic synthetic nucleoside analogue and an antiviral agent. Intracellularly, A-Bec (Abacavir) is converted by cellular enzymes to the active metabolite carbovir triphosphate, an analogue of deoxyguanosine-5'-triphosphate (dGTP). Carbovir triphosphate inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA. Viral DNA growth is terminated because the incorporated nucleotide lacks a 3'-OH group, which is needed to form the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation.

Dosage and Administration:

Use A-Bec (Abacavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· A-Bec (Abacavir) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get A-Bec (Abacavir) refilled.

· Take A-Bec (Abacavir) by mouth with or without food.

· Taking A-Bec (Abacavir) at the same time(s) each day will help you remember to take it.

Ask your health care provider any questions you may have about how to use A-Bec (Abacavir).

 

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; lack of energy; loss of appetite; mild nausea; tiredness; trouble sleeping; unusual dreams; vomiting.

Precaution:

Before taking A-Bec (Abacavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems (such as hepatitis B or C, or cirrhosis), kidney problems, alcohol use.

Store:

Store A-Bec (Abacavir) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Do not freeze. Store away from heat, moisture, and light. Keep A-Bec (Abacavir) out of the reach of children and away from pets.

Warning:

A-Bec (Abacavir) is a prescription drug and should be used under proper medical guidance and advice. The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

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Efamat 600 Mg Tablet

Efamat 600 Mg Tablet
  • Efamat 600 Mg Tablet
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Approx. Price: Rs 1,893 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 tablet
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)200MG,300MG,600MG
UsageClinical, Hospital, Personal

Product Details:

Packaging Size30 Tablet Packaging Type Strips Dose/Strength (ex. 1 Mg Or 1 Ml)200 300 Mg Usage Hospital/ Personal -Minimum Order Quantity1Item Code: 89897302UsesEfamat 600 mg tablet is used in combination with other medications for the treatment of human immunodeficiency virus (HIV) infection.How it works

Efamat 600 mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood.

Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.
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Efferven 600 (MG) Tablet

Efferven 600 (MG) Tablet
  • Efferven 600 (MG) Tablet
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Approx. Price: Rs 2,382 / Bottle

Product Details:

Product Type Finished ProductDose600 Mg Packaging Size30 Tablet Minimum Order Quantity1Item Code: 89898617UsesEfferven 600mg tablet is used in combination with other medications for the treatment of human immunodeficiency virus (HIV) infection.How it works

Efferven 600mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood.

Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.
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  • Minimum Order Quantity: 1 Bottle
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Efcure

Efcure
  • Efcure
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Approx. Price: Rs 2,382 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablets per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)600Mg
UsageClinical, Hospital, Personal

Product Details:

Packaging Size30 TABLETPackaging TypeBOTTLEDose/Strength (ex. 1 Mg Or 1 Ml)600 MGUsageHospital/ Personal -Minimum Order Quantity1Item Code: 89899763UsesEfcure 600mg tablet is used in combination with other medications for the treatment of human immunodeficiency virus (HIV) infection.How it works

Efcure 600mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood.

Common side effectsDepression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.
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Erlocip (Erlotinib)

Erlocip (Erlotinib)
  • Erlocip (Erlotinib)
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Approx. Price: Rs 6,660 / Bottle

Product Details:

Dose100 Mg Usage Hospital/ Personal -Packaging Size30 Tablet Packaging Type Bottle Item Code: 83675767

 

Erlocip (Erlotinib)

Brand name: Erlocip

Active Ingeridents(Generic Name) : Erlotinib

Company Name: Cipla

Package: 30 taps

Strength: 100mg

Indication:

It is used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer. It is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

Mechanism of action:

Erlotinib is an epidermal growth factor receptor inhibitor (EGFR inhibitor). The drug follows Iressa (gefitinib), which was the first drug of this type. Erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor.[1] For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer. These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes. When erlotinib binds to EGFR, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated.

Dosage and Administration:

Use erlotinib as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take erlotinib by mouth with a glass of water on an empty stomach at least 1 hour before or 2 hours after eating.

· Wash your hands immediately after taking erlotinib.

· Take erlotinib on a regular schedule to get the most benefit from it. Taking erlotinib at the same time each day will help you to remember to take it.

· If you miss a dose of erlotinib, contact your doctor right away.

Side effects:

Important things to remember about the side effects of erlotinib:

The following side effects are common (occurring in greater than 30%) for patients taking Erlotinib:

  • Rash , Diarrhea, Poor appetite, Fatigue, Shortness of breath, Cough, Nausea and vomiting

These side effects are less common side effects (occurring in about 10-29%) of patients receiving Erlotinib:

  • Infection, Mouth sores, Itching, Dry skin, Eye irritation, Abdominal pain

Precaution:

· Before starting erlotinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Certain medications can interfere with the levels/effects of erlotinib. It is important your oncologist is aware of all medications. Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.

Store: Erlotinibroom temperature away from moisture and heat.

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Trustiva Tablets

Trustiva Tablets
  • Trustiva Tablets
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Approx. Price: Rs 3,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablets Per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)600mg/300mg/200mg
UsageClinical, Hospital, Personal

Product Details:

Minimum Order Quantity1Item Code: 70922908We provide the optimum Trustiva Tablets largely used in severe diseases and are supplied on the large market scale. 
Specifications:
  • Trade Name Trustiva Manufacturer Gen X (Hetero Healthcare Ltd)Unit600mg/300mg/200mgTypeTablet.
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INSTGRA (dolutegravir)

INSTGRA (dolutegravir)
  • INSTGRA (dolutegravir)
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Approx. Price: Rs 2,500 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablets Per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)Dolutegravir 50mg
UsageClinical, Hospital, Personal

INSTGRA (Dolutegravir) Brand name: INSTGRA Active Ingeridents(Generic Name) : Dolutegravir Company Name: Emcure Package: 30 Tablets/Bottles Strength :50mg Indication:Dolutegravir (DTG) is an FDA-approved drug  for the treatment of HIV infection. Dolutegravir is an integrase inhibitor. Mechanism of action:INSTGRA (Dolutegravir)is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. INSTGRA (Dolutegravir)has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.Dosage and Administration:Use Instgra (Dolutegravir)as directed by your doctor. Check the label on the medicine for exact dosing instructions.
• An extra patient leaflet is available with INSTGRA (Dolutegravir). Talk to your pharmacist if you have questions about this information.
• Take INSTGRA (Dolutegravir)by mouth with or without food.
• Do not take an antacid or product that has magnesium, aluminum, iron, or calcium in it; sucralfate; or buffered medicines within 6 hours before or 2 hours after you take dolutegravir.
Side effects:All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:Headache; tiredness; trouble sleeping.Store:Store INSTGRA (Dolutegravir)at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep INSTGRA (Dolutegravir)out of the reach of children and away from pets.
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Dolutegravir Tivicay

Dolutegravir Tivicay
  • Dolutegravir Tivicay
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Approx. Price: Rs 9,750 / Bottle

Product Details:

Minimum Order Quantity1 Bottle
Packaging Size30 Tablets Per Bottle
Packaging TypeBottle
Dose/Strength (ex. 1 mg or 1 ml)50mg
UsageClinical, Hospital, Personal

What is Dolutegravir: Dolutegravir (DTG) is an FDA-approved drug. it is used for the treatment and the management of HIV infection. Dolutegravir is an integrase inhibitor.By blocking integrase, integrase inhibitors prevent HIV from multiplying and can reduce the amount of HIV in the body. 

Mode Of Action:Dolutegravir is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity.  

Dosage:

Population

Recommended Dose

Treatment naive or treatment experienced INSTI-naive

50mg once daily

Treatment-Naive or Treatment INSTI-naïve when coadministered with certain UGT1A or CYP3A inducers

50mg twice daily

 

 

INSTI-Experienced with certain INSTI-associated resistence Substitution or clinically Suspected

INSTI Resistence.

50mg twice daily

 

 

 

 

Side Effects:

· Hypersensitivity reactions.

· Effects on serum liver biochemistries in patients with hepatitis B or C co-infection .

· Fat Redistribution

· Immune Reconstitution Syndrome

· Trouble sleeping.

· Tiredness.

· Headache.
Warnings Contraindications

Coadministration with due to the potential for increased plasma concentrations and the risk for serious and/or life-threatening events.

Cautions: Hypersensitivity reactions reported; characterized by rash, constitutional findings, and sometimes organ dysfunction, including liver injury.


Patients with underlying hepatitis B or C may be at increased risk for worsening or development of transaminase elevations.


Inducers of UGT1A1 and CYP3A (eg, oxcarbazepine, phenytoin, phenobarbital, carbamazepine, St John’s wort, rifampin) decreased dolutegravir.

StorageStore dolutegravir at room temperature, 68°F to 77°F (20°C to 25°C).

Keep dolutegravir out of reach of children.

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