Apple Pharmaceuticals

Description:
Lenvaheal 10 contains Lenvatinib 10mg is an oral multi-kinase inhibitor, available in 10mg capsule form, used in the treatment of certain types of cancer, such as thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma. It works by inhibiting angiogenesis and tumor cell proliferation.

 

Uses:
Lenvaheal 10 - Lenvatinib 10mg capsule is indicated for the treatment of:

• Differentiated thyroid cancer (DTC) that is refractory to radioactive iodine treatment
• Advanced renal cell carcinoma (in combination with other agents)
• Unresectable hepatocellular carcinoma

 

Metabolism:
Lenvatinib is metabolized primarily in the liver, mainly via cytochrome P450 enzymes (CYP3A). It undergoes oxidation and demethylation, with the main circulating metabolite being an inactive form.

 

Adverse Effects:
Common adverse effects include:

• Hypertension
• Fatigue
• Diarrhea
• Decreased appetite
• Weight loss
• Nausea
• Stomatitis
  Serious side effects may include arterial thromboembolic events, liver impairment, and proteinuria.

Distribution:
Lenvatinib is highly protein-bound (approximately 98-99%) in plasma. The volume of distribution is moderate, indicating some tissue penetration.

 

Excretion:
Lenvatinib and its metabolites are excreted mainly via feces (about 64%), with a smaller portion excreted in urine (approximately 25%). The elimination half-life is about 28 hours.

 

Dosage:
The recommended starting dose for adults varies depending on the cancer type and combination with other drugs. For differentiated thyroid cancer, the usual starting dose is 24 mg orally once daily. Dose adjustments may be required based on tolerability and adverse reactions.

 

Product Introduction : Pertuza 420mg Injection is an anticancer medication containing the active constituent Pertuzumab. It is used to treat a type of breast cancer (HER2-positive breast cancer) in combination with other chemotherapy medications. Cancer is a condition in which cells multiply uncontrolled and abnormally.
Pertuza 420mg Injection is not recommended for adolescents and children under 18 years of age. Before taking this medicine, it is vital to inform your doctor if you have or have ever had heart problems or chemotherapy. Use effective birth control during the treatment and for at least six months after the last dose. 
Inform your doctor if you have kidney disease before starting with this Pertuzumab injection. Patients with kidney disease should cautiously use this medicine. Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with this medicine. Do not stop taking this medication without talking to your physician first. 
Uses of Pertuza 420mg Injection

• HER2-positive breast cancer

Therapeutic Effects of Pertuza 420mg Injection
Pertuza 420mg binds to the human epidermal growth factor receptor 2 (HER2) on cancer cells, potentially destroying or inhibiting cancer cell growth.
Interaction of Pertuza 420mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Pertuza 420mg and reduce effectiveness by causing undesirable side effects.  
More Information about Pertuza 420mg Injection

• Store in refrigerator at 2°C to 8°C. Do not freeze.
• Keep Perjeta 420mg Injection out of sight and reach of children.

Side Effects of Pertuza 420mg Injection

• Low white blood cell count
• Heart problems (cough, swelling in arms or legs, shortness of breath)
• Tumour lysis syndrome (confusion, tiredness, irregular heartbeat, seizures, tingling sensation)
• Infusion reactions (fever, chills, hot flushes, nausea, headache, joint, and muscle pain)
• Severe allergic reactions (swelling of throat and face, difficulty in breathing)
• Severe or persistent diarrhea

Common side effect

• Rash
• Changes in taste
• Hair loss

Additional Information:

• Delivery Time: Immediately
• Packaging Details: 1 vial 420mg/14ml Injection