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Minimum Order Quantity: 3 Unit
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Brand | Sofovir |
Dosage Form | Tablet |
Composition | Sofosbuvir |
Drug Name | Sofovir |
Active Ingredient | Sofosbuvir |
Usage/Application | Hep C |
Packaging Type | Bottle |
Indications | Hep C |
Packaging Size | 1x28 |
Dose/Strength | 400 mg |
Manufactured By | Hetero |
Marketed By | Hetero |
Application | Hep C |
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Packaging Size | 28 Tablets |
Strength | 400mg |
Composition | Sofosbuvir 400mg |
Treatment | Hepatitis C virus Infection (HCV) |
Prescription/Non prescription | Prescription |
Brand | Sofocure |
Manufacturer | Emcure Pharmaceuticals Ltd |
Form | Tablet |
Shelf life | 2 Years |
Therapeutic Uses | Hepatitis C virus Infection (HCV) |
Sofocure contains an anti viral agent known as Sofosbuvir The anti-viral agents is most probably used for treating chronic hepatitis C viral infection caused by genotypes I, II, III or IV. Sofocure fixed dose combination structural protein inhibitors like NS5B.
INDICATIONSofocure contains an anti viral agent known as Sofosbuvir The anti-viral agents is most probably used for treating chronic hepatitis C viral infection caused by genotypes I, II, III or IV. Sofocure fixed dose combination structural protein inhibitors like NS5B.
ADMEAbsorption :
The peak plasma concentration time of Sofosbuvir is 0.5 to 1 hour
Distribution :
Sofosbuvir plasma protein binding capacity 61 to 65%
Metabolism :
The metabolism of both Sofocure is occurs hepatically Sofosbuvir: cathepsin A, carboxyl esterase 1 or HINT1
Elimination :Half life of Sofosbuvir is 0.4 hour & GS-331007: 27 hours Sofosbuvir: 80% through urine, 14% through feces.
Sofocure CAUSES UNDESIRABLE EFFECTS
Headache Fatigue Nausea Asthenia Insomnia Anemia HBV reactivation Elevation of lipase & amylase levels Elevation of creatine kinase Cardiac disorder like bradycardia while concomitant with amiodarone Angioedema Skin rashes
Sofocure Tablets Manufacture & Marketed by Emcure Pharmaceuticals Limited
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Dosage Form | Tablet |
Usage | Hospital, Clinical |
Packaging Type | Bottle |
Composition | Sofosbuvir 400mg & Ledipasvir 90mg |
Indications | Hepatitis C virus ( HCV) |
Packaging Size | 1x28 |
Brand | Myhep Lvir |
Application | Hepatitis C |
We are manfacturer,trader & supplier of Myhep Lvir tablet. Myhep Lvir tablet should be used for both adults & pediatric patients with the age of 12 years or older or weight of at least 35kg. Used for; Genotype I, 4, 5, or 6 with compensated cirrhosis or without cirrhosis Genotype 1 infection with compensated cirrhosis or without cirrhosis Liver transplantation condition, genotype 1 with decompensated cirrhosis by use of ribavirin Genotype 1 or 4 without cirrhosis or with compensated cirrhosis by use of ribavirin Pediatric patients, HCV infection related to genotype 1, 4, 5, or 6 without cirrhosis or with compensated cirrhosis.
Dosage and Administration
The usual advised dose of Myhep Lvir is one tablet should be administered as once a day. In HIV-1 co infected patients, Myhep Lvirdosage consideration is; Patient without cirrhosis: (adult or pediatric of 12 years of age or older with genotype I, IV, V or VI Chronic HCV) The prescribed dose of Myhep Lvir is one tablet should be taken orally as a single dose for 12 weeks
Genotype IWithout cirrhosis or compensated cirrhosis: Myhep Lvir should be taken alone as a single dose followed for 12 weeks
Therapy experienced without cirrhosis: Myhep Lvir should be taken as a single agent for once a day for 12 weeks
Therapy experienced with compensated cirrhosis: Myhep Lvir tablet should be used for 24 weeks
In decompensated cirrhosis: Myhep Lvir should be combined with ribavirin to be used, followed for 12 weeks
Genotype I to IVIn liver transplantation patients with compensated cirrhosis or without cirrhosis: Myhep Lvir tablet should be combined with ribavirin for 12 weeks.
Genotype IV, V or VI :
Myhep Lvir tablets should be administered alone for 12 weeks for Without cirrhosis or with compensated cirrhosis patients: On the basis of body weight the dose of ribavirin should be calculated <75kg: 1000mg; ≥75kg: 1200mg Ribavirin should be administered with food.
Mechanism of action :
Ledipasvir is a solid prohibitor of perpetual hepatitis C viral relating non structural 5A protein which is a viral phosphoprotein. The essential part of ledipasvir in hostile to viral action instrument; Restraint of; Replication Virion assembly Secretion The mechanism of sofosbuvir associated with against viral movement is; Sofosbuvir is prohibitor of nucleotide analogue of hepatitis C viral disease identified with non basic 5B polymerase. This catalyst is in charge of interceding the HCV RNA duplication. The dynamic type of sofosbuvir is in triphosphate shape, which included diminishing the common cell uridine nucleotide and is coordinated by HCV RNA polymerase into the broadened RNA preliminary strand, which is closed in viral chain end.
PHARMACOKINETICS
Peak plasma concentration of Myhep Lvir :
Sofosbuvir: 0.8 to 1 hour & GS331007: 3.5 to 4 hours; ledipasvir: 4 to 4.5 hours No effect produced, while Myhep Lvirshould be administered with or without food.
Plasma protein binding capacity of Myhep Lvir :
Sofosbuvir: 61 to 65% & GS-331007: minimal binding effect, ledipasvir: >99.8%
Metabolism of Myhep Lvir :
Sofosbuvir: hepatic metabolism with cathepsin A, or carboxyl esterase 1 & ledipasvir: mediated by CYP1A2, 2C8, 2C9, 2C19, 2D6 & 3A4.
Elimination of Myhep Lvir : Major route of elimination is through urine & feces. Ledipasvir through urine by 87%; sofosbuvir through urine by 80%, feces by 14% & exhaled air by 3.5%
side effect :
Elevation of bilirubin , lipase , creatine kinase Severe bradycardia HBV reactivation Chest pain Dizziness Trouble in breathing Fatigue Headache Nausea Diarrhea Insomnia
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Dosage Form | Tablet |
Dose/Strength (ex. 1 mg or 1 ml) | Ledipasvir 90mg & Sofosbuvir 400mg |
Packaging Type | Bottle |
Composition | Sofosbuvir 400mg & Ledipasvir 90mg |
Indications | Hepatitis C |
Packaging Size | 1x28 |
Brand | Strides |
Application | Hepatitis C |
Indication:
Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.
Mechanism of action:
Dosage and Administration:
Side effects:
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Minimum Order Quantity: 1 Bottle
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Dosage Form | Tablet |
Composition | Sofosbuvir & Ledipasvir |
Drug Name | Ledviclear |
Active Ingredient | Sofosbuvir & Ledipasvir |
Brand | Abbott |
Indications | Hep C |
Dose/Strength | 400mg & 100mg |
Usage/Application | Hep C |
We are manfacturer,trader & supplier of Ledviclear tablet. Uses of Ledviclear Tablet
Ledviclear 90mg/400mg Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.
How Ledviclear Tablet works
Ledviclear 90mg/400mg Tablet is a combination of two antiviral medicines: Ledipasvir and Sofosbuvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.
How to use Ledviclear Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ledviclear 90mg/400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
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Minimum Order Quantity: 1 Bottle
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Packaging Size | 1X28 |
Strength | 90mg/400mg |
Composition | Ledispasvir 90mg & Sofosbuvir 400mg |
Treatment | Hepatitis C virus infecton (HCV) |
Prescription/Non prescription | Prescription |
Brand | Ledikast |
Manufacturer | Natco Pharma Ltd |
Form | Tablet |
Shelf life | 2 years |
Therapeutic Uses | Hepatitis C virus infecton (HCV) |
The usual advised dose of Ledikast is one tablet should be administered as once a day. In HIV-1 co infected patients, Ledifos dosage consideration is; Patient without cirrhosis: (adult or pediatric of 12 years of age or older with genotype I, IV, V or VI Chronic HCV) The prescribed dose of Ledikast is one tablet should be taken orally as a single dose for 12 weeks.
Genotype IWithout cirrhosis or compensated cirrhosis: Ledikast should be taken alone as a single dose followed for 12 weeks
Therapy experienced without cirrhosis:Ledikast should be taken as a single agent for once a day for 12 weeks
Therapy experienced with compensated cirrhosis: Ledikast tablet should be used for 24 weeks
In decompensated cirrhosis: Ledifos should be combined with ribavirin to be used, followed for 12 weeks
In liver transplantation patients with compensated cirrhosis or without cirrhosis: Ledikast tablet should be combined with ribavirin for 12 weeks.
Genotype IV, V or VI :
Ledikast tablets should be administered alone for 12 weeks for Without cirrhosis or with compensated cirrhosis patients: On the basis of body weight the dose of ribavirin should be calculated <75kg: 1000mg; ≥75kg: 1200mg Ribavirin should be administered with food. Ledikast should be administered with or without food.
LEDIKAST SIDE EFFECTS
Elevation of bilirubin Elevation of lipase Elevation of creatine kinase Severe bradycardia HBV reactivation Chest pain Dizziness Trouble in breathing Fatigue Headache Nausea Diarrhea Insomnia
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Packaging Size | 28 Tablets |
Strength | 60mg |
Composition | Daclatasvir 60mg |
Treatment | Hepatitis C Virus Infections (HCV) |
Prescription/Non prescription | Prescription |
Brand | Daclacure |
Manufacturer | Emcure Phamaceuticals Ltd |
Form | Tablet |
Shelf life | 2 Years |
Therapeutic Uses | Hepatitis C Virus Infections (HCV) |
Daclacure is belongs to class like;
Anti-hepaciviral drug
HCV NS5A protein inhibitor
Daclacure is a NS5A protein inhibitor, NS5A is a HCV non structural phosphoprotein that is responsible for replicating function of charge of viral RNA augmentation on endoplasmic reticulum membranes. Daclacure has ability to merge to viral RNA. There are two pathway involved in the mechanism of Daclacure; Cis acting function of basally phosphorylated NS5A is responsible for maintaining the HCV replication complex. HCV assembly & infectious particle formation is altered by Trans acting function of hyperphosphorylated NS5A. Daclacure is used to confuse the hyperphosphorylated NS5A proteins thus concludes as interceding with activity of newly produced HCV. Daclacure works as blockade of; Intercellular viral RNA synthesis Virion assembly/ secretion in-vivo
SIDE EFFECTS OF DACLACURE
While using the drug Some common side effects occurred as follows:: Chest pain, dizziness Irregular heart beat Unusual tiredness More common: Headache, nausea Pharmacological effects:
Daclacure manufacture and marketed by Emcure Pharmaceuticals Limited
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Packaging Size | 30 Tablets In Bottle |
Strength | 60mg |
Composition | Daclatasvir 60mg |
Treatment | Hepatitis C Virus Infection (HCV) |
Prescription/Non prescription | Prescription |
Brand | Hepcifix |
Manufacturer | Dr.Reddys Laboratories Ltd |
Form | Tablet |
Shelf life | 2 Years |
Therapeutic Uses | Hepatitis C Virus Infection (HCV) |
Hepcifix is belongs to class like;
Anti-hepaciviral drug
HCV NS5A protein inhibitor
Hepcifix is a NS5A protein inhibitor, NS5A is a HCV non structural phosphoprotein that is responsible for replicating function of charge of viral RNA augmentation on endoplasmic reticulum membranes. Hepcifix has ability to merge to viral RNA. There are two pathway involved in the mechanism of Hepcifix; Cis acting function of basally phosphorylated NS5A is responsible for maintaining the HCV replication complex. HCV assembly & infectious particle formation is altered by Trans acting function of hyperphosphorylated NS5A. Hepcifixa is used to confuse the hyperphosphorylated NS5A proteins thus concludes as interceding with activity of newly produced HCV. Hepcifix works as blockade of; Intercellular viral RNA synthesis Virion assembly/ secretion in-vivo
Hepcifix Side effects are Difficulty in breathing,Swelling face or lips,Chest pain & Light headed feeling
Hepcifix manufactured and Marketed by Dr. Reddys Laboratories Ltd
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Packaging Size | 1x28 |
Strength | 60mg |
Composition | Daclatasvir 60mg |
Treatment | Hepatitis C virus infection (HCV) |
Prescription/Non prescription | Prescription |
Brand | Dacikast-60 |
Manufacturer | Natco Pharma Ltd |
Form | Tablet |
Shelf life | 2 years |
Therapeutic Uses | Hepatitis C virus infection (HCV) |
Dacikast-60 is belongs to class like;
Anti-hepaciviral drug
HCV NS5A protein inhibitor
Dacikast-60 is a NS5A protein inhibitor, NS5A is a HCV non structural phosphoprotein that is responsible for replicating function of charge of viral RNA augmentation on endoplasmic reticulum membranes. Dacikast-60 has ability to merge to viral RNA. There are two pathway involved in the mechanism of Mydekla; Cis acting function of basally phosphorylated NS5A is responsible for maintaining the HCV replication complex. HCV assembly & infectious particle formation is altered by Trans acting function of hyperphosphorylated NS5A. Dacikast-60 is used to confuse the hyperphosphorylated NS5A proteins thus concludes as interceding with activity of newly produced HCV. Dacikast-60 works as blockade of; Intercellular viral RNA synthesis Virion assembly/ secretion in-vivo
SIDE EFFECTS OF Dacikast-60
While using the drug Some common side effects occurred as follows:: Chest pain, dizziness Irregular heart beat Unusual tiredness More common: Headache, nausea Pharmacological effects:
OTHER
Pyrexia , hot flush, loss of weight, Fatigue, asthenia, influenza like symptoms
NERVEHeadache, migraine, somnolence
DERMATOLOGICALRashes, Pruritus, dry skin, alopecia, and Erythema multiforme
PSYCHIATRICInsomnia, irritability, depression, anxiety
BLOODAnemia, neutropenia, thrombocytopenia, esinophillia
RESPIRATORYCough, Nasopharyngitis, dyspnea, nasal congestion, upper respiratory infection
GITGastro esophageal reflux, vomiting, Abdominal pain, elevated lipase, flatulence
MUSCLEMyalgia, arthralgia, back pain
METABOLICLoss of appetite
CVSBradycardia, heart block, cardiac arrhythmias
LIVERIncreased AST & ALT, Hyperbilirubinaemia, hepatitis B reactivation
GENITOURINARYUrinary tract infection
OCULARDry eye
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Dosage Form | Tablet |
Dose/Strength (ex. 1 mg or 1 ml) | 60mg |
Packaging Size | 1x28 |
Packaging Type | Bottle |
Usage | Personal, Clinical, Hospital |
Composition | Daclatasvir 60mg |
Indications | Hepatitis C |
Application | Hepatitis C |
Brand | Hepcdac |
Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.
Mechanism of action:the dimeric symmetry of these compounds suggests that they act on a dimer of ns5a, which is also consistent with the presence of dimers in crystals of ns5a domain 1 from genotype 1b. Genotype 1a hcv is less potently affected by these compounds and resistance mutations have a greater effect than in the 1b genotypes. We have obtained crystals of domain 1 of the important 1a ns5a homologue and intriguingly, our x-ray crystal structure reveals two new dimeric forms of this domain. Furthermore, the high solvent content (75%) makes it ideal for ligand-soaking. Daclatasvir (dcv) shows twofold symmetry suggesting ns5a dimers may be of physiological importance and serve as potential binding sites for dcv. These dimers also allow for new conformations of a ns5a expansive network which could explain its operation on the membranous web. Additionally, sulfates bound in the crystal structure may provide evidence for the previously proposed rna binding groove, or explain regulation of ns5a domain 2 and 3 function and phosphorylation. Dosage and administration:take daclatasvir exactly as your healthcare provider tells you to.· do not change your dose unless your healthcare provider tells you to.· do not stop taking daclatasvir without first talking with your healthcare provider.· take daclatasvir 1 time each day with or without food.The recommended usage of daclatasvir to treat chronic hepatitis c virus is 60 mg taken orally once daily with or without food in combination with sofosbuvir. The recommended treatment duration is 12 weeks. Side effects:tiredness, headache, nausea, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Precaution: before taking daclatasvir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Store: daclatasvir room temperature away from moisture and heat.Additional Information:
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Composition | Tacrolimus 1mg |
Manufacturer | Concord Biotech |
Treatment | - Prevention of organ rejection in transplant patients |
Prescription/Non prescription | Prescription |
Brand | Tacrocord 1mg |
Strength | 1mg |
Packaging Size | 10 capsules in a strip |
Dose/Strength | 1mg |
We are manfacturer,trader & supplier of Tacrocord 1mg Capsule. Tacrocord 1mg Capsule is used along with other medicines to prevent your body rejecting a new organ (e.g., liver, kidney or heart) after transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body’s immune system, so it does not attack the new organ.
The amount of Tacrocord 1mg Capsule you take and how often you take it depends on the type of transplant you have, your body weight and what other medicines you are taking. Follow your doctor’s instructions carefully. You should take it on an empty stomach, at least 1 hour before or 2 hours after a meal. Take this medicine regularly to get the maximum benefit and keep taking it, even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ.
Tacrocord 1mg Capsule has many potential side effects. It can cause or worsen diabetes and kidney and liver problems. These need urgent medical attention. Other common side effects include nausea, stomach pain, diarrhea and difficulty sleeping. If these or other side effects do not go away or get worse, tell your doctor. Because it lowers your immune system, you may also catch more infections than usual.
Before taking this medicine, tell your doctor if you have kidney, liver or heart problems, diabetes or high blood pressure. Also let your doctor know what other medications you are taking, especially for infections, pain, and arthritis. These and others may affect, or be affected by, this medicine. You should limit your exposure to the sun and UV (ultraviolet) light while taking it because immunosuppressants could increase your risk of skin cancer.
Both men and women using this medicine should use effective birth control to prevent pregnancy. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed. Before and during treatment you will need frequent medical tests to monitor your progress, and your blood pressure will need to be checked often.
USES OF Tacrocord 1MG CAPSULE
· Prevention of organ rejection in transplant patients
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Packaging Size | 1x28 |
Strength | 400mg |
Dosage Form | Tablet |
Brand | Abbott |
Treatment | Hepatitis C virus infection (HCV) |
Composition | Sofosbuvir |
Drug Name | Viroclear |
Prescription/Non prescription | Prescription |
Usage/Application | Hepatitis C virus infection (HCV) |
Brand Name | Viroclear |
Active Ingredient | Sofosbuvir |
Manufacturer | Abbott India Ltd |
Form | Tablet |
Uses | Hep C virus infection (HCV) |
Packaging Type | Bottle |
Dose/Strength | 400 mg |
Manufactured By | Hetero |
Marketed By | Abbott |
Application | Hep C |
We are manfacturer,trader & supplier of Viroclear Tablets. Viroclear contains an anti viral agent known as Sofosbuvir The anti-viral agents is most probably used for treating chronic hepatitis C viral infection caused by genotypes I, II, III or IV. Viroclear fixed dose combination structural protein inhibitors like NS5B.
INDICATIONViroclear is used for the treatment of chronic hepatitis C viral infection associated with genotype I II,III or IV In decompensated cirrhosis, Viroclear tablets are combined with ribavirin Viroclear is majorly indicated for hepatitis C viral infection therapy by combining with other anti-viral medicines. Viroclear mainly prescribed for adolescent patients, and for pediatric patients with age of 12 years or weighing at least 35kg in genotype II or III induced hepatitis C infection.
MECHANISM
Viroclear Sofosbuvir Sofosbuvir is pharmacologically categorized as uridine monophosphate analogue prohibitor of HCV polymerase. The mechanism of action of Sofosbuvir is basically involved in RNA replicates inhibitor. Sofosbuvir is available as prodrug which gets converted into an active uridine triphosphate and inserted the active moiety into viral RNA by NS5B polymerase enzyme causes chain elimination.
VIROCLEAR CAUSES UNDESIRABLE EFFECTS
Headache Fatigue Nausea Asthenia Insomnia Anemia HBV reactivation Elevation of lipase & amylase levels Elevation of creatine kinase Cardiac disorder like bradycardia while concomitant with amiodarone Angioedema Skin rashes
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Strength | 60mg |
Dosage Form | Tablet |
Brand | Daclahep |
Treatment | Hepatitis C virus infections (HCV) |
Composition | Daclatasvir 60mg |
Prescription/Non prescription | Prescription |
Drug Name | Daclahep |
Manufacturer | Hetero health care ltd |
Usage/Application | Hep C |
Form | Tablet |
Packaging Size | 1x28 |
Packaging Type | Bottle |
Indications | Hepatitis C |
Dose/Strength | 60mg |
Manufactured By | Hetero health care limited |
Marketed By | Hetero |
Application | Hepatitis C |
Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.
SIDE EFFECTS OF DACLAHEP
While using the drug Some common side effects occurred as follows:: Chest pain, dizziness Irregular heart beat Unusual tiredness More common: Headache, nausea Pharmacological effects:
OTHERPyrexia , hot flush, loss of weight, Fatigue, asthenia, influenza like symptoms
NERVEHeadache, migraine, somnolence
DERMATOLOGICALRashes, Pruritus, dry skin, alopecia, and Erythema multiforme
PSYCHIATRICInsomnia, irritability, depression, anxiety
BLOODAnemia, neutropenia, thrombocytopenia, esinophillia
RESPIRATORYCough, Nasopharyngitis, dyspnea, nasal congestion, upper respiratory infection
GITGastro esophageal reflux, vomiting, Abdominal pain, elevated lipase, flatulence
MUSCLEMyalgia, arthralgia, back pain
METABOLICLoss of appetite
CVSBradycardia, heart block, cardiac arrhythmias
LIVERIncreased AST & ALT, Hyperbilirubinaemia, hepatitis B reactivation
GENITOURINARYUrinary tract infection
OCULARDry eye
Daclahep manufactured & Marketed by Hetero health care
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Brand | Hepcvir L |
Packaging Size | 28 Tablets |
Dosage Form | Tablet |
Dose/Strength | 400mg & 90mg |
Usage | Hospital, Clinical |
Packaging Type | Bottle |
Composition | Sofosuvir 400mg & Ledipasvir 90mg |
Indications | Hepatitis C |
Application | Hepatitis C |
Sofosbuvir and Ledipasvir is a combination and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Sofosbuvir & Ledipasvir tablets, may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir ledipasvir , ledipasvir and sofosbuvir , ledipasvir and sofosbuvir cost, ledipasvir & sofosbuvir tablets, sofosbuvir ledipasvir price.
Mechanism of action:
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Composition | Ribavirin 200mg |
Form | capsules |
Packaging Size | 14 strips of 10 caps (14 x 10 caps) |
Usage/Application | HBV and HCV |
Brand Name | Heptos 200mg |
Dosage | 200mg |
Type Of Medicines | Allopathic |
Strength | 200mg |
Brand | Heptos 200mg |
Feature | HBV and HCV |
Drug Name | Ribavirin |
Content | Ribavirin |
Manufactured By | Hetero Healthcare Ltd |
Medicine Type | anti-viral |
Salt | Ribavirin |
We are manfacturer,trader & supplier of Heptos 200mg Capsules.
Heptos 200mg ( Ribavirin)
Brand name: Heptos 200mg
Active Ingeridents(Generic Name) : Ribavirin
Company Name: Hetero Healthcare Ltd
Package: 140 capsules in a box
Strength : 200mg
Indication:
Heptos 200mg( Ribavirin) is used in combination with other antiviral medications to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. Heptos 200mg ( Ribavirin) works by reducing the amount of hepatitis C virus in your body, which may help your liver recover.
Mechanism of action:
Heptos 200mg ( Ribavirin) is readily phosphorylated intracellularly by adenosine kinase to Heptos 200mg ( Ribavirin) mono-, di-, and triphosphate metabolites. Heptos 200mg ( Ribavirin) triphosphate (RTP) is a potent competitive inhibitor of inosine monophosphate (IMP) dehydrogenase, viral RNA polymerase and messenger RNA (mRNA) guanylyltransferase (viral) and can be incorporated into RNA in RNA viral species.. Guanylyltranserase inhibition stops the capping of mRNA. These diverse effects result in a marked reduction of intracellular guanosine triphosphate (GTP) pools and inhibition of viral RNA and protein synthesis. Heptos 200mg ( Ribavirin) is also incorporated into the viral genome causing lethal mutagenesis and a subsequent decrease in specific viral infectivity.
Dosage and Administration:
Use Heptos 200mg ( Ribavirin) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
· Heptos 200mg ( Ribavirin) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Heptos 200mg ( Ribavirin) refilled.
· Take Heptos 200mg(Ribavirin) by mouth with food.
· Drinking extra fluids while you are taking Heptos 200mg ( Ribavirin) is recommended. Check with your doctor for instructions.
Ask your health care provider any questions you may have about how to use Heptos 200mg ( Ribavirin).
Side effects:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; dizziness; dry mouth; dry skin; hair loss; joint pain; loss of appetite; mild headache, nausea, or vomiting; mild stomach pain; tiredness; trouble sleeping; upset stomach; weakness or fatigue.
Precaution:
Before taking Heptos 200mg ( Ribavirin), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Store:
Store Heptos 200mg ( Ribavirin) between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Heptos 200mg ( Ribavirin) out of the reach of children and away from pets.
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Product Brochure
Strength | 400mg |
Dosage Form | Tablet |
Composition | Sofosbuvir 400mg |
Treatment | Hepatitis C Virus Infection (HCV) |
Prescription/Non prescription | Prescription |
Drug Name | Hepcinat |
Manufacturer | Natco Pharma Ltd |
Active Ingredient | Sofosbuvir 400mg |
Usage/Application | Hepatitis C ( HCV ) |
Form | Tablet |
Pack Size | 28 Tablets |
Dose/Strength (mg or ml) | 400 mg |
Packaging Size | 1x28 |
Indications | Hepatitis C ( HCV ) |
Packaging Type | Bottle |
Shelf life | 2 years |
Therapeutic Uses | Hepatitis C Virus Infection (HCV) |
Dose/Strength | 400mg |
Manufactured By | Natco Ltd |
Marketed By | Natco Ltd |
Brand | Hepcinat 400mg |
We are manfacturer,trader & supplier of Hepcinat 400mg Tablets.Hepcinat 400mg Tablets contains Sofosbuvir 400mg
Hepcinat 400mg Sofosbuvir 400mg tablets is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online.
Indication of Hepcinat 400mg :
It is used for the treatment of hepatitis Cvirus (HCV) infection..
Mechanism of action of Hepcinat 400mg
Dosage and Administration of Hepcinat 400mg :
Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition and response to treatment.
This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time each day.
How to use Hepcinat Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepcinat 400 mg Tablet is to be taken with food.
Side effects:
Hepcinat 400mg is manufactured and Marketed by Natco Ltd
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Packaging Size | 28 Tablets |
Strength | 400mg |
Composition | Sofosbuvir 400mg |
Treatment | Hepatitis C |
Prescription/Non prescription | Prescription |
Form | Tablet |
Brand | Myhep |
Manufacturer | Mylan |
Shelf life | LoNG |
Country of Origin | Made in India |
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Packaging Size | 28 Tablets |
Strength | 400mg |
Composition | Sofosbuvir 400mg |
Treatment | Hepatitis C |
Prescription/Non prescription | Prescription |
Form | Tablet |
Brand | Resof |
Manufacturer | Dr.Reddys |
Shelf life | LoNG |
Country of Origin | Made in India |
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Dosage Form | Tablet |
Brand | SoviHep |
Form | Tablets |
Composition | Sofosbuvir 400mg |
Prescription/Non prescription | Prescription |
Drug Name | Sovihep 400mg |
Packaging Size | 28 Tablets |
Brand Name | Sovihep 400mg |
Packaging Type | Bottle |
Dosage | 400mg |
Active Ingredient | Sofosbuvir 400mg |
Manufacturer | Natco Pharma Ltd |
Usage/Application | Hepatitis C virus |
Indications | Hepatitis C Virus ( HCV) |
Dose/Strength | 400mg |
Manufactured By | Zydus |
Marketed By | Zydus |
Application | Hepatitis C Virus ( HCV) |
We are manfacturer,trader & supplier of Sovihep 400mg Tablets
Sovihep 400mg Tablets contains Sofosbuvir 400mg
Sovihep 400mg Sofosbuvir 400mg tablets is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online.
Indication of Sovihep 400mg :
It is used for the treatment of hepatitis Cvirus (HCV) infection..
Mechanism of action of Sovihep 400mg
Dosage and Administration of Sovihep 400mg
Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition and response to treatment.
This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time each day.
How to use Sovihep 400mg Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepcinat 400 mg Tablet is to be taken with food.
Side effects:
Sovihep 400mg is manufactured and Marketed by Zydus cadila Ltd
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Packaging Size | 1X28 |
Strength | 400MG |
Composition | Sofosbuvir 400mg |
Treatment | Hepatitis C virus infection ( HCV) |
Prescription/Non prescription | Prescription |
Brand | Sofokast |
Manufacturer | Natco Pharma Ltd |
Form | Tablet |
Shelf life | 2 years |
Therapeutic Uses | Hepatitis C virus infection ( HCV) |
Sofokast contains an anti viral agent known as Sofosbuvir The anti-viral agents is most probably used for treating chronic hepatitis C viral infection caused by genotypes I, II, III or IV. Sofokast fixed dose combination structural protein inhibitors like NS5B.
ADME
Absorption :
The peak plasma concentration time of Sofosbuvir is 0.5 to 1 hour
Distribution :
Sofosbuvir plasma protein binding capacity 61 to 65%
Metabolism :
The metabolism of both Sofokast is occurs hepatically Sofosbuvir: cathepsin A, carboxyl esterase 1 or HINT1
Elimination :
Half life of Sofosbuvir is 0.4 hour & GS-331007: 27 hours Sofosbuvir: 80% through urine, 14% through feces.
SOFOKAST CAUSES UNDESIRABLE EFFECTS
Headache Fatigue Nausea Asthenia Insomnia Anemia HBV reactivation Elevation of lipase & amylase levels Elevation of creatine kinase Cardiac disorder like bradycardia while concomitant with amiodarone Angioedema Skin rashes
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Minimum Order Quantity: 1 Bottle
Product Brochure
Packaging Size | 28 tablets in a bottle |
Strength | sofosbuvir 400mg + Daclatasvir 60mg |
Composition | sofosbuvir 400mg + Daclatasvir 60mg |
Form | Tablets |
Treatment | Hepatitis C Virus Infection |
Prescription/Non prescription | Prescription |
Usage/Application | Hepatitis C Virus |
Brand Name | Hepcinat Plus |
Brand | Hepcinat Plus |
Dosage | 460mg |
Manufacturer | Natco Pharma Ltd |
Packaging Type | 28 tablets in a bottle |
We are manfacturer,trader & supplier of Hepcinat Plus Tablets.Hepcinat Plus tablets are hostile to viral medicine Hepcinat Plus tablets are single measurements treatment, it is a doctor prescribed medication utilized by the patients just under the information of restorative expert who are all around rehearsed Daclatasvir isn''''''''''''''''t utilized alone, for better activity it ought to be joined with Sofosbuvir tablet. In some condition Hepcinat Plus is joined with ribavirin, a hostile to viral pharmaceutical utilized as a part of decompensated (Child Pugh B or C) cirrhosis
Indication :
The primary sign of Hepcinat Plus is; This mix tablets are utilized to treat the constant hepatitis C viral disease caused by genotype I or III The significant restriction happened while utilizing Hepcinat Plus tablets are lessening of steady virological reaction rate in hepatitis C genotype I or III contaminated patients.
Mechanism of action :
The activity of Hepcinat Plus tablets are occurred by involving in some mechanism;
SOFOSBUVIR
Sofosbuvir containing sofosbuvir has hostile to hepaciviral movement, which is specifically acting medication displays its activity by disallowing NS5B RNA dependent RNA polymerase protein; fundamental for hepatitis viral duplication. Sofosbuvir is processed to frame uridine triphosphate, a fundamental dynamic metabolite which uncovered a hostile to viral action. The mixture of this dynamic metabolite into hepatitis viral RNA with the assistance of NS5B polymerase and causes viral chain cessation
DACLATASVIR
Daclatasvir containing Daclatasvir removes hostile to viral action by restricting NS5A protein which is needful in viral generation and virion collection
DOSAGE
Hepcinat Plus tablets are given with or without food, in the condition of chronic hepatitis C viral infection originated by genotype I or III Hepcinat Plus is single dose therapy
Dosage regimensDaclatasvir normally is not used alone treatment, it is combined with Sofosbuvir The suggested dosage of Hepcinat Plus is one tablet should be taken as a single dose If Sofosbuvir is discontinued, Daclatasvir also get stopped Genotype I Patient suffered without cirrhosis or with compensated cirrhosis: The recommended usual dosage of Hepcinat Plus is one tablet should be taken as a single dose with or without food In decompensated cirrhosis patients: Hepcinat Plus should be altogether with ribavirin as a single dose
Genotype IIIPatient suffered without cirrhosis or with compensated cirrhosis: The recommended usual dosage of Hepcinat Plus is one tablet should be administered as a single dose with or without food In decompensated cirrhosis patients: Hepcinat Plus should be concomitant with ribavirin as a once a day The dosage of ribavirin; The hemoglobin level of patients, dose can be calculated on basis of body weight. Below 75kg: The dosage is 1000mg of ribavirin; suggested for genotype I or III 600mg of ribavirin as an primary dose and followed as 1000mg/per Slightly 75 kg: The dose of 1200mg of ribavirin administrated In decompensated cirrhosis given as twice daily.
SIDE EFFECTS
Side effects occurred in Hepcinat Plus tablet receiving patients such as; Fatigue Headache Insomnia Nausea Pruritus Asthenia Anemia Loss of appetite Flu like syndrome Pyrexia Diarrhea Rash Neutropenia Myalgia Irritability Pancytopenia Increase of creatine kinase, bilirubin, lipase, AST & ALT HBV reoccurrence may occurs Serious bradycardia while combining with amiodarone
Hepcinat Plus is manufactured by Natco Pharma Ltd
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Form | Tablet |
Usage/Application | Hepatitis C (HCV) |
Brand Name | Hepcvir 400mg |
Dosage | Sofosbuvir 400mg |
Brand | Hepcvir |
Packaging Size | 1x28 |
Dose/Strength (ex. 1 mg or 1 ml) | 400mg |
Dosage Form | Tablet |
Packaging Type | Bottle |
Usage | Bottle |
Composition | Sofosbuvir 400mg |
Indications | Hepatitis C ( HCV ) |
Type Of Medicines | Allopathic |
Application | Hepatitis C ( HCV) |
Dose/Strength (e.g. 1 mg ) | 400 mg |
We are manfacturer,trader & supplier of Hepcvir 400mg Tablets. Hepcvir 400mg Tablets contains Sofosbuvir 400mg
Hepcvir 400mg Sofosbuvir 400mg tablets is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online.
Indication of Hepcvir 400mg :
It is used for the treatment of hepatitis Cvirus (HCV) infection..
Mechanism of action of Hepcvir 400mg
Dosage and Administration of Hepcvir 400mg :
Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition and response to treatment.
This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time each day.
How to use Hepcvir Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepcvir 400 mg Tablet is to be taken with food.
Side effects:
Hepcvir 400mg is manufactured and Marketed by Cipla Ltd
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Minimum Order Quantity: 1 Bottle
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Brand | Natdac |
Dosage Form | Tablet |
Composition | Daclatasvir 60mg |
Drug Name | Natdac |
Active Ingredient | Daclatasvir |
Usage/Application | Hep C |
Indications | Hepatitis C |
Dose/Strength | 60mg |
Manufactured By | Natco |
Marketed By | Natco |
Application | Hepatitis C |
Packaging Size | 1x28 |
Packaging Type | Bottle |
We are manfacturer,trader & supplier of Natdac 60mg tablet. Natdac 60mg contains the active ingredient Daclatasvir 60mg which is used to treat the Chronic Hepatitis C infection(HCV) along with the other drugs. Natdac 60mg is the class of anti-viral drug. Natdac 60mg mostly used with the combiantion of sofosbuvir 400mg ,may be with or without ribavirin.Natdac 60mg usual course of the treatment is 12 weeks to 24 weeks treatments depends upon the HCV count.Natdac 60mg works in the blood for certain period of time to remove the virus from the blood.
Natdac 60mg -Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir 60mg tablet should never be used without sofosbuvir. These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.
Indication of Natdac 60mg:
Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.
Dosage and Administration:
Side effects:Tiredness, headache, nausea, or diarrhea may occur.
Natdac 60mg is manufactured and marketed by Natco Ltd
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Strength | 60mg |
Composition | Daclatasvir 60mg |
Treatment | Hepatitis C |
Prescription/Non prescription | Prescription |
Brand | Mydacla,Mydacla 60mg |
Manufacturer | MYLAN LTD |
Form | Tablet |
Dose/Strength (e.g. 1 mg ) | 60mg |
Packaging Size | 28 Tablets |
We are manfacturer,trader & supplier of Mydacla 60mg Tablets.Mydacla 60mg contains the active ingredient Daclatasvir 60mg which is used to treat the Chronic Hepatitis C infection(HCV) along with the other drugs. Mydacla 60mg is the class of anti-viral drug. Mydacla 60mg mostly used with the combiantion of sofosbuvir 400mg ,may be with or without ribavirin.Mydacla 60mg usual course of the treatment is 12 weeks to 24 weeks treatments depends upon the HCV count.Mydacla 60mg works in the blood for certain period of time to remove the virus from the blood.
Mydacla 60mg -Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. Daclatasvir 60mg tablet should never be used without sofosbuvir. These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.
Indication of Mydacla 60mg:
Daclatasvir is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.
Dosage and Administration:
Side effects:Tiredness, headache, nausea, or diarrhea may occur.
Mydacla 60mg is manufactured and marketed by Mylan Ltd
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Brand | DaciHep |
Dosage Form | Tablet |
Composition | Daclatasvir 60mg |
Drug Name | Dacihep |
Active Ingredient | Daclatasvir |
Usage/Application | Hep C |
Packaging Size | 1x28 |
Packaging Type | Bottle |
Indications | Hepatitis C |
Dose/Strength | 60mg |
Manufactured By | cadila |
Marketed By | Zydus |
Application | Hepatitis C |
Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.
Mechanism of action:
Side effects:
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Packaging Size | 1X28 |
Strength | 400mg/60mg |
Composition | Sofosbuvir 400mg & Daclatasvir 60mg |
Treatment | Hepatitis C virus infection (HCV) |
Prescription/Non prescription | Prescription |
Brand | Sofokast-Plus |
Manufacturer | Natco Pharma Ltd |
Form | Tablet |
Shelf life | 2 years |
Therapeutic Uses | Hepatitis C virus infection (HCV) |
The primary sign of Sofokast-Plus is; This mix tablets are utilized to treat the constant hepatitis C viral disease caused by genotype I or III The significant restriction happened while utilizing Sofokast-Plus tablets are lessening of steady virological reaction rate in hepatitis C genotype I or III contaminated patients.
PHARMACOLOGYThe activity of Sofokast-Plus tablets are occurred by involving in some mechanism;
SOFOSBUVIR
Sofosbuvir containing sofosbuvir has hostile to hepaciviral movement, which is specifically acting medication displays its activity by disallowing NS5B RNA dependent RNA polymerase protein; fundamental for hepatitis viral duplication. Sofosbuvir is processed to frame uridine triphosphate, a fundamental dynamic metabolite which uncovered a hostile to viral action. The mixture of this dynamic metabolite into hepatitis viral RNA with the assistance of NS5B polymerase and causes viral chain cessation
DACLATASVIR
Daclatasvir containing Daclatasvir removes hostile to viral action by restricting NS5A protein which is needful in viral generation and virion collection
SOFOKAST - PLUS SIDE EFFECTS
Side effects occurred in Sofokast-Plus tablet receiving patients such as; Fatigue Headache Insomnia Nausea Pruritus Asthenia Anemia Loss of appetite Flu like syndrome Pyrexia Diarrhea Rash Neutropenia Myalgia Irritability Pancytopenia Increase of creatine kinase, bilirubin, lipase, AST & ALT HBV reoccurrence may occurs Serious bradycardia while combining with amiodarone
Additional Information:
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