HIV Medicine

Product Details:

Viraday Uses

Viraday Tablet is used for Hiv, Hiv infection, Hepatitis b virus and other conditions

Viraday Tablet contains Efavirenz, Emtricitabine and Tenofovir as active ingredients.

Viraday Tablet works by lowering the growth and decreasing the amount of HIV virus in the body; blocking the activity of a viral enzyme; blocking RNA-dependent DNA polymerase function in viral DNA replication;

Cipla manufactures Viraday Tablet.

 

Product Details:

Trustiva Uses:

Trustiva Tablet is used for Hiv, Hiv infection, Hepatitis b virus and other conditions.

Trustiva Tablet contains Efavirenz, Emtricitabine and Tenofovir as active ingredients.

Trustiva Tablet works by lowering the growth and decreasing the amount of HIV virus in the body; blocking the activity of a viral enzyme; blocking RNA-dependent DNA polymerase function in viral DNA replication;

Hetero Healthcare (Genx) manufactures Trustiva Tablet.

 

Product Details:

Uses

Tenofovir alafenamide is used to treat chronic hepatitis B infection, a viral infection of the liver. It works by stopping or slowing the growth of the virus. Chronic hepatitis infection can lead to serious liver damage (cirrhosis) and liver cancer.

How to use Tenofovir Alafenamide Fumarate Tablet

Before starting treatment with this medication, your doctor should test you for HIV infection. If you have HIV infection along with hepatitis B infection, tenofovir alafenamide should not be used alone since this may make it harder to treat your HIV infection. Combination drug treatment should always be used to treat HIV infection.

 

Read the Patient Information Leaflet if available from your pharmacist before you start taking tenofovir alafenamide, and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Product Details:

Uses of Tafnat Tablet

Tafnat 25 mg Tablet is used in the treatment of HIV infectionand chronic hepatitis B virus (HBV) infection.

 

How Tafnat Tablet works

 

Tafnat 25 mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

 

 

How to use Tafnat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tafnat 25 mg Tablet is to be taken with food.

 

Product Details:

Uses of Telura Tablet

Telura Tablet is used in the treatment of HIV infection.

 

 

How Telura Tablet works

 

Telura Tablet is a combination of three antiviral medicines: Lamivudine, Tenofovir disoproxil fumarate and Efavirenz. They work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

 

How to use Telura Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Telura Tablet is to be taken empty stomach.
Taking this medicine with food increases the risk of side effects.

 

Product Details:

Teevir Uses

 

Teevir Tablet is used for Hiv, Hiv infection, Hepatitis b virus and other conditions..

Teevir Tablet contains Efavirenz, Emtricitabine and Tenofovir as active ingredients.

Teevir Tablet works by lowering the growth and decreasing the amount of HIV virus in the body; blocking the activity of a viral enzyme; blocking RNA-dependent DNA polymerase function in viral DNA replication;

Mylan Pharma manufactures Teevir Tablet.

Product Details:

Naivex Uses : Naivex tablet contains an active of Dolutegravir 50mg which prevents the multiplication of HIV virus in human body and stops the growth of HIV virus in blood.

 Naivex Side Effects : * Fatigue.
* Muscle pain
* Weakness
* Headache
* Nausea
* Diarrhea
* Depression

 

·         These side-effects are possible, but it does not always occur.  ·         Some of the side-effects may be rare but serious. Consult your doctor. ·         if you observe any of the following side-effects, especially if they do not go away.


* Disease of muscle tissue.
* Kidney problems.
* Low potassium levels.
* Lactic acidosis.
* Liver problems.
* Increased liver enzymes.

Naivex Storage :  * Store in a cool, dry place with below
* Keep your tablets in a safe place where children cannot see or reach them. Your tablets could harm them.

 

Product Details:

Uses

Tenofovir is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Tenofovir belongs to a class of drugs known as nucleotide reverse transcriptase inhibitors (NRTIs).

Tenofovir is also used to treat a certain type of liver infection called chronic hepatitis Binfection. It helps to decrease the amount of hepatitis B virus in your body by interfering with virus growth.

How to use Tenofovir Disoproxil Fumarate Tablet

Read the Patient Information Leaflet if available from your pharmacist before you start taking tenofovir, and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily.

The dosage is based on your medical condition, kidney function, and response to treatment. For children, the dosage is also based on weight.

 

Product Details:

Uses

Dolutegravir is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Dolutegravir belongs to a class of drugs known as integrase inhibitors. It blocks the virus from growing and infecting more cells.

How to use Dolutegravir Tablet

Read the Patient Information Leaflet if available from your pharmacist before you start taking dolutegravir and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually 1 to 2 times daily.

 

Product Details:

Brand Name : Spegra 
Active components :Dolutegravir,Emtricitabine & TAF
Manufactured by : Emcure
Category : HIV
Package : 30 tablets

Spegra tablets Is a combination of dolutegravir,emcitarabine,temnofovir alafenamide . Spegra belongs to the calss of agent known as anti-retroviral agents. Spegra tablet is used to treat HIV type I infection. Spegratablet preferred for HIV infection, it is non-curable and non-preventable. But the growth of HIV virus can be suppressed and leads to elevate immune cells .

Product Details:

Indication:

Empetus (Ritonavir) is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy . Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C.

Mechanism of action:

Empetus (Ritonavir) was originally developed as an inhibitor of HIV protease. It is one of the most complex inhibitors. It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors. More specifically, Empetus (Ritonavir) is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). The drug''s molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors. This discovery, which has drastically reduced the adverse effects and improved the efficacy of protease inhibitors and HAART, was first communicated in an article published in the journal AIDS in 1997 by researchers at the University of Liverpool. This effect does come with a price: it also affects the efficacy of numerous other medications, making it difficult to know how to administer them concurrently.

 

Dosage and Administration:

Use Empetus (Ritonavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· Take Empetus (Ritonavir) by mouth with meals.

· Swallow Empetus (Ritonavir) whole. Do not break, crush, or chew before swallowing.

· Continue to take Empetus (Ritonavir) even if you feel well. Do not miss any doses.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal skin sensations, especially around the mouth, fingers, and toes; diarrhea; headache; loss of appetite; mild stomach pain; nausea; taste changes; tiredness; vomiting; weakness.

Precaution:

Before taking Empetus (Ritonavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart problems (coronary artery disease, heart attack), hemophilia, high cholesterol/triglycerides, gout/high uric acid in the blood, liver problems (such as hepatitis B, hepatitis C), pancreatitis

 

Store:

Store Empetus (Ritonavir) in the original container at room temperature up to 86 degrees F (30 degrees C). If stored outside of the original container, throw away any part not used after 2 weeks. Storage at temperatures up to 122 degrees F (50 degrees C) is permitted for up to 7 days. Store away from heat, moisture, and light.

Product Details:

Indication:

• Treating HIV infection in certain patients along with other antiretroviral medicines.
• Daruvir (Darunavir) must always be taken along with another medicine called ritonavir.
• Daruvir (Darunavir) is an HIV protease inhibitor.
• It works by blocking the growth of HIV.

Mechanism of action:

• Daruvir (Darunavir) is a HIV protease inhibitor which prevents HIV replication by binding to the enzyme''s active site, thereby preventing the dimerization and the catalytic activity of the HIV-1 protease.
• Daruvir (Darunavir) selectively inhibits the cleavage of HIV encoded Gag-Pol polyproteins in virus-infected cells, which prevents the formation of mature infectious virus particles. Structual analyses suggests that the close contact that Daruvir (Darunavir) has with the main chains of the protease active site amino acids (Asp-29 and Asp-30) is an important contributing factor to its potency and wide spectrum of activity against multi-protease inhibitor resistant HIV-1 variants. Daruvir (Darunavir) can also adapt to the changing shape of a protease enzyme because of its molecular flexibility.
• Daruvir (Darunavir) is known to bind to two distinct sites on the enzyme: the active site cavity and the surface of one of the flexible flaps in the protease dimer.

Side effects:

• Since Daruvir (Darunavir) is always taken with other HIV medications, it may be difficult to tell whether Daruvir (Darunavir) is causing certain side effects.
• However, Daruvir (Darunavir) is known to cause diarrhea, nausea, vomiting, stomach pain, and headache.
• If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

• Before taking Daruvir (Darunavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
• Since Daruvir (Darunavir) must be taken with ritonavir, tell your doctor if you are allergic to ritonavir.
• This product may contain inactive ingredients, which can cause allergic reactions or other problems.
• Talk to your pharmacist for more details.

Store:

• Store Daruvir (Darunavir) at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted.
• Store away from heat, moisture, and light.

Product Details:

Nevimune (Nevirapine)

Brand name: Nevimune

Active Ingeridents(Generic Name) : Nevirapine

Company Name: Cipla

Package:60 Tablets/Bottle

Strength : 200mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Nevimune (Nevirapine) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Mechanism of action:

Nevimune (Nevirapine) falls in the non-nucleoside reverse transcriptase inhibitor (NNRTI) class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme''s active site, NNRTIs bind allosterically at a distinct site away from the active site termed the NNRTI pocket.

Nevimune (Nevirapine) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

Resistance to Nevimune (Nevirapine) develops rapidly if viral replication is not completely suppressed. The most common mutations observed after Nevimune (Nevirapine) treatment are Y181C and K103N, which are also observed with other NNRTIs. As all NNRTIs bind within the same pocket, viral strains which are resistant to Nevimune (Nevirapine) are usually also resistant to the other NNRTIs, efavirenz and delavirdine. However, second generation NNRTIs like rilpivirine and etravirine are effective in treatment for HIV strains resistant to Nevimune (Nevirapine) and other first generation drugs in that same class.

Dosage and Administration:

Use Nevimune (Nevirapine) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Nevimune (Nevirapine) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Nevimune (Nevirapine) refilled.

· Take Nevimune (Nevirapine) by mouth with or without food.

· Taking Nevimune (Nevirapine) at the same time each day will help you remember to take it.

· Continue to take Nevimune (Nevirapine) even if you feel well. Do not miss any doses.

Side effects:

Tiredness, nausea, vomiting, or diarrhea may occur. Drowsiness may rarely occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Nevimune (Nevirapine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems (such as hepatitis B or C, cirrhosis), kidney dialysis, lactose or galactose intolerance.

Store:

Store Nevimune (Nevirapine) at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light.

Product Details:

Efamat 600 mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood. Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.

Product Details:

We are counted among the leading manufacturer, trader, exporter and supplier of best quality Lamivir Tablets that is widely used for the treatment of chronic hepatitis B. Owing to its effectiveness; our offered tablets are highly demanded in the market. At our premises, our offered tablets are processed using quality assured chemical compounds that are sourced from the reliable vendors of the market. Additionally, these tablets can get by our clients from us at reasonable prices.

Product Details:

Item Code: 85672320

Emletra (Lopinavir /Ritonavir)

Brand name: Emletra

Active Ingeridents(Generic Name) : Lopinavir / Ritonavir

Company Name: Emcure

Package : 60 tablets

Strength : Lopinavir 200mg+ Ritonavir 50mg

Indication:

Treating HIV infection. It is used along with other medicines for HIV. Emletra (Lopinavir /Ritonavir) is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

 

Mechanism of action:

Lopinavir:

Lopinavir inhibits the HIV viral protease enzyme. This prevents cleavage of the gag-pol polyprotein and, therefore, improper viral assembly results. This subsequently results in non-infectious, immature viral particles

Ritonavir :

Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

Dosage and Administration:

Use Emletra (Lopinavir /Ritonavir) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Emletra (Lopinavir /Ritonavir) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Emletra (Lopinavir /Ritonavir) refilled.

· Take Emletra (Lopinavir /Ritonavir) by mouth with or without food.

· Swallow Emletra (Lopinavir /Ritonavir) whole. Do not break, crush, or chew before swallowing.

· Emletra (Lopinavir /Ritonavir) must be taken with other HIV medicines to be effective.

· If you are also taking didanosine, you may take it at the same time as Emletra (Lopinavir /Ritonavir) without food.

· Taking Emletra (Lopinavir /Ritonavir) at the same time each day will help you remember to take it.

Ask your health care provider any questions you may have about how to use Emletra (Lopinavir /Ritonavir).

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; headache; muscle or joint pain; nausea; stomach pain; tiredness; vomiting; weakness.

Precaution:

Before taking this product, tell your doctor or pharmacist if you are allergic to either lopinavir or ritonavir; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details

 

Store:

Store Emletra (Lopinavir /Ritonavir) at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light.

Product Details:

Item Code: 83994383

Efavir (Efavirenz)

Brand name: Efavir

Active Ingeridents(Generic Name) : Efavirenz

Company Name: Cipla

Package: 30 Tablets/Bottle

Strength : 600mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Efavir (Efavirenz) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Mechanism of action:

Efavir (Efavirenz) falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme''s active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.

Efavir (Efavirenz) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

Dosage and Administration:

Use Efavir (Efavirenz) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take Efavir (Efavirenz) by mouth on an empty stomach. Taking Efavir (Efavirenz) with food, especially with a high-fat meal, may lead to increased blood levels of Efavir (Efavirenz). This may increase your risk of side effects.

· Take Efavir (Efavirenz) with a full glass of water (8 oz [240 mL]).

· Swallow Efavir (Efavirenz) whole. Do not break, crush, or chew before swallowing. If you cannot swallow Efavir (Efavirenz) whole, tell your doctor.

· Do NOT take more than the recommended dose, change your dose, or stop taking Efavir (Efavirenz) without checking with your doctor.

· Take Efavir (Efavirenz) at the same time every day, preferably at bedtime unless otherwise directed by your doctor.

· Continue to use Efavir (Efavirenz) even if you feel well. Do not miss any doses.

 

Side effects:

Dizziness, trouble sleeping, drowsiness, unusual dreams, and trouble concentrating may frequently occur. These side effects may begin 1-2 days after starting this medication and usually go away in 2-4 weeks. They are also reduced by taking Efavir (Efavirenz) on an empty stomach at bedtime. Avoid alcohol and street drugs while taking Efavir (Efavirenz). They may worsen these side effects. Tiredness, headache, nausea, vomiting, and diarrhea may also occur.

Precaution:

Before taking Efavir (Efavirenz), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Store:

Store Efavir (Efavirenz) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container away from heat, moisture, and light.

Product Details:

Item Code: 85671748

Duovir (Zidovudine /Lamivudine)

Brand name: Duovir

Active Ingeridents(Generic Name) : Zidovudine /Lamivudine

Company Name: Cipla

Package :60 Tablets /Bottle

Strength : Zidovudine 300mg + Lamivudine 150mg

Indication:

Duovir (Zidovudine /Lamivudine) are antiviral medications that prevent human immunodeficiency virus (HIV) cells from multiplying in your body.

Duovir (Zidovudine /Lamivudine) is a combination medicine used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AID.

 

 

Mechanism of action:

Zidovudine:

Zidovudine, a structural analog of thymidine, is a prodrug that must be phosphorylated to its active 5′-triphosphate metabolite, zidovudine triphosphate (ZDV-TP). It inhibits the activity of HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleotide analogue. It competes with the natural substrate dGTP and incorporates itself into viral DNA. It is also a weak inhibitor of cellular DNA polymerase α and γ.

Lamivudine:

Lamivudine is a synthetic nucleoside analogue and is phosphorylated intracellularly to its active 5'-triphosphate metabolite, lamivudine triphosphate (L-TP). This nucleoside analogue is incorporated into viral DNA by HIV reverse transcriptase and HBV polymerase, resulting in DNA chain termination.

Dosage and Administration:

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Duovir (Zidovudine /Lamivudine) can be taken with or without food.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Side effects:

Headache, tiredness, loss of appetite, nausea, vomiting, diarrhea, trouble sleeping, dizziness, or stuffy nose may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Precaution:

Before taking Duovir (Zidovudine /Lamivudine), tell your doctor or pharmacist if you are allergic to either drug; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems (such as hepatitis B or C, cirrhosis), disease of the pancreas (pancreatitis), alcohol use, low red/white blood cell counts.

Store: Duovir (Zidovudine /Lamivudine) room temperature away from moisture and heat or cold. Do not freeze.

Product Details:

Item Code: 85673776

 

Atazor-R (Atazanavir / Ritonavir )

Brand name: Atazor-R 

Active Ingeridents(Generic Name) : Atazanavir / Ritonavir

Company Name: Emcure

Package : 30 Tablets/Bottle

Strength : Atazanavir 300mg + Ritonavir 100mg

Indication:

Treating HIV infection. It is used along with other medicines for HIV. Atazor-R (Atazanavir / Ritonavir )is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

 

 

Mechanism of action:

Atazanavir:

Atazanavir selectively inhibits the virus-specific processing of viral Gag and Gag-Pol polyproteins in HIV-1 infected cells by binding to the active site of HIV-1 protease, thus preventing the formation of mature virions. Atazanavir is not active against HIV-2.

Ritonavir :

Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

 

Dosage and Administration:

· An extra patient leaflet is available with Atazor-R (Atazanavir / Ritonavir ). Talk to your pharmacist if you have questions about this information.

· Take Atazor-R (Atazanavir / Ritonavir )by mouth with or without food.

· Continue to take Atazor-R (Atazanavir / Ritonavir )even if you feel well. Do not miss any doses.

· Taking Atazor-R (Atazanavir / Ritonavir )at the same time each day will help you remember to take it.

· If you miss a dose of Atazor-R (Atazanavir / Ritonavir ), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

Below are the common side effects that may occur when using Atazor-R (Atazanavir / Ritonavir )Tablet. Please consult your doctor if you observe any of these side effects even in mild form.

· Abdominal pain , Accumulation of body fat, Anxiety, Asthma

 

Precaution:

Take the following precautions or be careful about the following while consuming Atazor-R (Atazanavir / Ritonavir ) Tablet:

· Children , Consult a doctor if you have haemophilia or pancreatitis, Kidney problems

 

store: Atazor-R (Atazanavir / Ritonavir )room temperature away from moisture and heat or cold. Do not freeze.

Product Details:

Item Code: 83994504

LamivirHBV (Lamivudine)

Brand name: LamivirHBV

Active Ingeridents(Generic Name) : Lamivudine

Company Name: Cipla

Package:10 Tablets

Strength : 100mg

Indication:

This drug is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. LamivirHBV (Lamivudine) belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.

Mechanism of action:

LamivirHBV (Lamivudine) is an analogue of cytidine. It can inhibit both types of HIV reverse transcriptase and also the reverse transcriptase of hepatitis B virus. It is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3''-OH group in the incorporated nucleoside analogue prevents the formation of the 5'' to 3'' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

LamivirHBV (Lamivudine) is administered orally, and it is rapidly absorbed with a bio-availability of over 80%. Some research suggests that LamivirHBV (Lamivudine) can cross the blood–brain barrier. LamivirHBV (Lamivudine) is often given in combination with zidovudine, with which it is highly synergistic. LamivirHBV (Lamivudine) treatment has been shown to restore zidovudine sensitivity of previously resistant HIV. LamivirHBV (Lamivudine) showed no evidence of carcinogenicity or mutagenicity in in vivo studies in mice and rats at doses from 10 to 58 times those used in humans.

Dosage and Administration:

Use LamivirHBV (Lamivudine) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Take LamivirHBV (Lamivudine) by mouth with or without food.

· Continue to take LamivirHBV (Lamivudine) even if you feel well. Do not miss any doses.

· Taking LamivirHBV (Lamivudine) at the same time each day will help you remember to take it.

· If you miss a dose of LamivirHBV (Lamivudine), take it as soon as possible. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

See also Warning section.

Headache, dizziness, nausea, diarrhea, or trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Precaution:

Before taking LamivirHBV (Lamivudine), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: pancreatitis, kidney problems, liver problems (such as hepatitis B or C, cirrhosis), alcohol use.

Store:

Store LamivirHBV (Lamivudine) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light.

Product Details:

Uses:

• Tenvir EM Tablet is used in combination with other antiretroviral medications for the treatment of HIV-1 infection in adults
• It is also used to treat chronic hepatitis B infection
• It may also be used for other conditions as determined by your doctor
• Tenvir–EM is an antiviral reverse transcriptase inhibitor
• It works to treat HIV infection by reducing the amount of HIV (the virus that causes AIDS) in the body by blocking the ability of the virus to multiply
• It works to treat HBV infection by reducing the amount of HBV in the body by blocking the ability of the virus to multiply and infect new liver cells
• Tenvir–EM is not a cure for HIV or AIDS.

Product Details:

Tenvir (Tenofovir )

Brand name: Tenvir

Active Ingeridents(Generic Name) : Tenofovir disoproxil Fumerate

Company Name: Cipla

Package:30 Tablets

Strength : 300mg

Indication:

Tenvir (Tenofovir ) is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life.

Mechanism of action:

Tenvir (Tenofovir ) is a defective adenosine nucleotide that selectively inhibits the action of reverse transcriptase, while only weakly interfering with mammalian DNA polymerases α, β, and mitochondrial DNA polymerase γ. Tenvir (Tenofovir ) prevents the formation of the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation. A phosphodiester bond cannot be formed because the Tenvir (Tenofovir ) molecule lacks an —OH group on the 3′ carbon of its deoxyribose sugar. Once incorporated into a growing DNA strand, Tenvir (Tenofovir ) causes premature termination of DNA transcription. The drug is classified as a nucleotide analogue reverse transcriptase inhibitor (NtRTI). Reverse transcriptase is a crucial viral enzyme in retroviruses such as human immunodeficiency virus (HIV) and in hepatitis B virus infections.

Dosage and Administration:

Use Tenvir (Tenofovir ) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· An extra patient leaflet is available with Tenvir (Tenofovir ). Talk to your pharmacist if you have questions about this information.

· Take Tenvir (Tenofovir ) by mouth with or without food.

· Continue to take Tenvir (Tenofovir ) even if you feel well. Do not miss any doses.

· Taking Tenvir (Tenofovir ) at the same time each day will help you remember to take it.

· Do not suddenly stop taking Tenvir (Tenofovir ) without checking with your doctor. This may cause the virus to become less sensitive to this or other medicines. If you have hepatitis B, your condition could become worse if you suddenly stop taking Tenvir (Tenofovir ).

· If you miss a dose of Tenvir (Tenofovir ), take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness; gas; headache; indigestion; loss of appetite; nausea; runny or stuffy nose; sweating; tiredness; trouble sleeping; vomiting; weakness; weight loss.

Precaution:

Before taking Tenvir (Tenofovir ), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

 

Store: Store Tenvir (Tenofovir ) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light.

Product Details:

Indication:

• Ritomune (Ritonavir) is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy.
• Often a low dose is used with other protease inhibitors.
• It may also be used in combination with other medications for hepatitis C.

Mechanism of action:

• Ritomune (Ritonavir) was originally developed as an inhibitor of HIV protease.
• It is one of the most complex inhibitors.
• It is now rarely used for its own antiviral activity, but remains widely used as a booster of other protease inhibitors.
• More specifically, Ritomune (Ritonavir) is used to inhibit a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4).
• The drug's molecular structure inhibits CYP3A4, so a low dose can be used to enhance other protease inhibitors.
• This discovery, which has drastically reduced the adverse effects and improved the efficacy of protease inhibitors and HAART, was first communicated in an article published in the journal AIDS in 1997 by researchers at the University of Liverpool.
• This effect does come with a price: it also affects the efficacy of numerous other medications, making it difficult to know how to administer them concurrently.

Precaution:

• Before taking Ritomune (Ritonavir), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
• This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart problems (coronary artery disease, heart attack), hemophilia, high cholesterol/triglycerides, gout/high uric acid in the blood, liver problems (such as hepatitis B, hepatitis C), pancreatitis

Store:

• Store Ritomune (Ritonavir) in the original container at room temperature up to 86 degrees F (30 degrees C).
• If stored outside of the original container, throw away any part not used after 2 weeks.
• Storage at temperatures up to 122 degrees F (50 degrees C) is permitted for up to 7 days.
• Store away from heat, moisture, and light.

Product Details:

Indication:

• This drug is used with other HIV medications to help control HIV infection.
• It helps to decrease the amount of HIV in your body so your immune system can work better.
• This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. A-Bec (Abacavir) belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.

Mechanism of action:

• A-Bec (Abacavir) is a carbocyclic synthetic nucleoside analogue and an antiviral agent.
• Intracellularly, A-Bec (Abacavir) is converted by cellular enzymes to the active metabolite carbovir triphosphate, an analogue of deoxyguanosine-5'-triphosphate (dGTP).
• Carbovir triphosphate inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.
• Viral DNA growth is terminated because the incorporated nucleotide lacks a 3'-OH group, which is needed to form the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation.

 

Side effects:

• All medicines may cause side effects, but many people have no, or minor, side effects.
• Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Warning:

• A-Bec (Abacavir) is a prescription drug and should be used under proper medical guidance and advice.
• The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.

Product Details:

Efferven 600mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood. Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.

Product Details:

Efcure 600 mg tablet belongs to a class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It inhibits the replication of HIV, thereby reducing the amount of the virus in the blood. Common side effects Depression, Nightmare, Impaired concentration, Indigestion, Insomnia, Vomiting, Diarrhoea, Headache, Nervousness, Abdominal pain, Rash, Suicidal thoughts, Dizziness, Stomach upset, Confusion, Memory loss.

Product Details:

Indication:

• It is used to treat non-small cell lung cancer (NSCLC), pancreatic cancer and several other types of cancer.
• It is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR).

Mechanism of action:

• Erlotinib is an epidermal growth factor receptor inhibitor (EGFR inhibitor).
• The drug follows Iressa (gefitinib), which was the first drug of this type.
• Erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer.
• It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor.
• For the signal to be transmitted, two EGFR molecules need to come together to form a homodimer.
• These then use the molecule of ATP to trans-phosphorylate each other on tyrosine residues, which generates phosphotyrosine residues, recruiting the phosphotyrosine-binding proteins to EGFR to assemble protein complexes that transduce signal cascades to the nucleus or activate other cellular biochemical processes.
• When erlotinib binds to EGFR, formation of phosphotyrosine residues in EGFR is not possible and the signal cascades are not initiated.

Precaution:

• Before starting erlotinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
• Certain medications can interfere with the levels/effects of erlotinib.
• It is important your oncologist is aware of all medications.
• Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.

Product Details:

What is Dolutegravir: Dolutegravir (DTG) is an FDA-approved drug. it is used for the treatment and the management of HIV infection. Dolutegravir is an integrase inhibitor.By blocking integrase, integrase inhibitors prevent HIV from multiplying and can reduce the amount of HIV in the body.

Product Details:

Indication:

• Duovir (Zidovudine /Lamivudine) are antiviral medications that prevent human immunodeficiency virus (HIV) cells from multiplying in your body.
• Duovir (Zidovudine /Lamivudine) is a combination medicine used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS).
• This medicine is not a cure for HIV or AID.

 

Mechanism of Action:

• Zidovudine, a structural analog of thymidine, is a prodrug that must be phosphorylated to its active 5′-triphosphate metabolite, zidovudine triphosphate (ZDV-TP).
• It inhibits the activity of HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleotide analogue.
• It competes with the natural substrate dGTP and incorporates itself into viral DNA.
• It is also a weak inhibitor of cellular DNA polymerase α and γ.

Dosage and Administration:

• Follow all directions on your prescription label.
• Do not take this medicine in larger or smaller amounts or for longer than recommended.
• Duovir (Zidovudine /Lamivudine) can be taken with or without food.
• HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor.
• Read the medication guide or patient instructions provided with each medication.
• Do not change your doses or medication schedule without your doctor's advice.
• Every person with HIV or AIDS should remain under the care of a doctor.

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