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Sofosbuvir and Ledipasvir

Sofosbuvir and Ledipasviris a medication used to treathepatitis C.It is a combination ofledipasvirandsofosbuvir.Cure rates are 94% to 99% in people infected withhepatitis C virus(HCV) genotype 1.Some evidence also supports use in HCV genotype 3 and 4.It is taken daily by mouth for 8–24 weeks.

  • Ledifos Tablets
  • Ledifos Tablets
  • Ledifos Tablets
Ledifos Tablets

Ledifos Tablets

Rs 6,500  / BottleGet Best Price

Minimum Order Quantity: 1 Bottle

StrengthLedispasvir 90mg & Sofosbuvir 400mg
BrandLedifos
Dosage FormTablet
TreatmentHepatitis C virus infection (HCV)
CompositionSofosbuvir 400mg & Ledipasvir 90mg
Prescription/Non prescriptionPrescription
Drug NameLedifos
Packaging Size28 Tablets in a bottle
Brand NameLedifos
Packaging TypeBottle
Active IngredientSofosbuvir & Ledipasvir
ManufacturerHetero Health Care Ltd
Usage/ApplicationHep C
FormTablet
Dose/Strength (mg or ml)90 mg & 400 mg
IndicationsHepatitis C
Dose/Strength400mg & 90mg
Manufactured ByHetero
Marketed ByHetero
ApplicationHepatitis C virus infection (HCV)
We are manfacturer,trader & supplier of    Ledifos Tablets.
Indication:
  • Treating chronic hepatitis C virus (HCV) infection in certain patients. Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents. It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Sofosbuvir and Ledipasvir is a combination and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Sofosbuvir & Ledipasvir tablets, may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir ledipasvir , ledipasvir and sofosbuvir , ledipasvir and sofosbuvir cost, ledipasvir & sofosbuvir tablets, sofosbuvir ledipasvir price.

Mechanism of action:

  • Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion.
  • Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase the key enzyme mediating HCV RNA replication.
  • The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.
Ledifos Tablets manufactured  by Hetero Health care Ltd

Additional Information:

  • Item Code: 75997115
  • Pay Mode Terms: T/T (Bank Transfer)
  • Port of Dispatch: Mumbai
  • Production Capacity: 2 years
  • Delivery Time: Immediate
  • Packaging Details: 28 Tablets in a Bottle

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Resof L Tablets

Resof L Tablets

Rs 7,500  / BoxGet Best Price

Minimum Order Quantity: 1 Box

StrengthSofosbuvir 400mg & Ledispasvir 90mg
TreatmentHepatitis C virus Iinfection (HCV)
Prescription/Non prescriptionPrescription
Usage/ApplicationHepatitis C virus Iinfection (HCV)
Brand NameResof L Tablets
ManufacturerDr.Reddy.s Laboratories Ltd
FormTablet
Dosage FormTablet
Packaging TypeBottle
CompositionSofosbuvir 400mg & Ledipasvir 90mg
IndicationsHepatitis C
ApplicationHepatitis C
BrandDr.Reddys
Packaging Size1x28

We are manfacturer,trader & supplier of    Resof L Tablets.
Resof L tablet should be used for both adults & pediatric patients with the age of 12 years or older or weight of at least 35kg. Used for; Genotype I, 4, 5, or 6 with compensated cirrhosis or without cirrhosis Genotype 1 infection with compensated cirrhosis or without cirrhosis Liver transplantation condition, genotype 1 with decompensated cirrhosis by use of ribavirin Genotype 1 or 4 without cirrhosis or with compensated cirrhosis by use of ribavirin Pediatric patients, HCV infection related to genotype 1, 4, 5, or 6 without cirrhosis or with compensated cirrhosis.

DOSAGE

The usual advised dose of Resof L is one tablet should be administered as once a day. In HIV-1 co infected patients, Resof L dosage consideration is; Patient without cirrhosis: (adult or pediatric of 12 years of age or older with genotype I, IV, V or VI Chronic HCV) The prescribed dose of Resof L is one tablet should be taken orally as a single dose for 12 weeks

Genotype I

 

Without cirrhosis or compensated cirrhosis: Resof L should be taken alone as a single dose followed for 12 weeks
Therapy experienced without cirrhosis: Resof L should be taken as a single agent for once a day for 12 weeks

Therapy experienced with compensated cirrhosis: Resof L tablet should be used for 24 weeks
In decompensated cirrhosis: Resof L should be combined with ribavirin to be used, followed for 12 weeks

Genotype I to IV

 

In liver transplantation patients with compensated cirrhosis or without cirrhosis: Resof L tablet should be combined with ribavirin for 12 weeks.
Genotype IV, V or VI :
Resof L tablets should be administered alone for 12 weeks for without cirrhosis or with compensated cirrhosis patients: On the basis of body weight the dose of ribavirin should be calculated <75kg: 1000mg; 75kg: 1200mg Ribavirin should be administered with food. Resof L should be administered with or without food.
SIDE EFFECTS 

Elevation of bilirubin Elevation of lipase Elevation of creatine kinase Severe bradycardia HBV reactivation Chest pain Dizziness Trouble in breathing Fatigue Headache Nausea Diarrhea Insomnia

Resof L Manufactured & Marketed by Dr.Reddy''s Laboratories Ltd



Additional Information:

  • Pay Mode Terms: T/T (Bank Transfer)
  • Port of Dispatch: Mumbai
  • Production Capacity: Large
  • Delivery Time: Immediate
  • Packaging Details: 28 Tablets in a Bottle

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  • Hepcinat-LP Tablets
  • Hepcinat-LP Tablets
  • Hepcinat-LP Tablets
Hepcinat-LP Tablets

Hepcinat-LP Tablets

Rs 8,500  / BottleGet Best Price

Minimum Order Quantity: 3 Bottle

Dosage FormTablet
CompositionSofosbuvir 400mg & Ledipasvir 90mg
Prescription/Non prescriptionPrescription
Drug NameHepcinat LP
Active IngredientSofosbuvir & Ledipasvir
Usage/ApplicationHep C
Packaging Size1x28
Packaging Typebottle
IndicationsHepatitis C
Dose/Strength400mg & 90mg
UsageHospital, Clinical
Manufactured ByNatco
Marketed ByNatco
Product TypeFinished Product
ApplicationHepatitis C
BrandNatco
Pack Size28 Tablet
We are manfacturer,trader & supplier of  Hepcinat-LP Tablets.
Indication:
  • Treating chronic hepatitis C virus (HCV) infection in certain patients.
  • Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents.
  • It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Sofosbuvir and Ledipasvir is a combination and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Sofosbuvir & Ledipasvir tablets, may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir ledipasvir , ledipasvir and sofosbuvir , ledipasvir and sofosbuvir cost, ledipasvir & sofosbuvir tablets, sofosbuvir ledipasvir price.

Mechanism of action:

  • Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion.
  • Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication.
  • The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.
Hepcinat Lp Manufactured & Marketed by Natco Pharma Ltd

Additional Information:

  • Pay Mode Terms: T/T (Bank Transfer)
  • Port of Dispatch: Mumbai
  • Delivery Time: Immediate

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  • Myhep LVIR Tablet ( Sofosbuvir 400mg & Ledipasvir 90mg Tablets - Mylan)
  • Myhep LVIR Tablet ( Sofosbuvir 400mg & Ledipasvir 90mg Tablets - Mylan)
  • Myhep LVIR Tablet ( Sofosbuvir 400mg & Ledipasvir 90mg Tablets - Mylan)
  • Myhep LVIR Tablet ( Sofosbuvir 400mg & Ledipasvir 90mg Tablets - Mylan)
  • Myhep LVIR Tablet ( Sofosbuvir 400mg & Ledipasvir 90mg Tablets - Mylan)
Myhep LVIR Tablet ( Sofosbuvir 400mg & Ledipasvir 90mg Tablets - Mylan)

Myhep LVIR Tablet ( Sofosbuvir 400mg & Ledipasvir 90mg Tablets - Mylan)

Rs 6,500  / UnitGet Best Price

Minimum Order Quantity: 1 Unit

Dosage FormTablet
UsageHospital, Clinical
Packaging TypeBottle
CompositionSofosbuvir 400mg & Ledipasvir 90mg
IndicationsHepatitis C virus ( HCV)
Packaging Size1x28
BrandMyhep Lvir
ApplicationHepatitis C

We are manfacturer,trader & supplier of  Myhep Lvir tablet. Myhep Lvir tablet should be used for both adults & pediatric patients with the age of 12 years or older or weight of at least 35kg. Used for; Genotype I, 4, 5, or 6 with compensated cirrhosis or without cirrhosis Genotype 1 infection with compensated cirrhosis or without cirrhosis Liver transplantation condition, genotype 1 with decompensated cirrhosis by use of ribavirin Genotype 1 or 4 without cirrhosis or with compensated cirrhosis by use of ribavirin Pediatric patients, HCV infection related to genotype 1, 4, 5, or 6 without cirrhosis or with compensated cirrhosis.

 Dosage and Administration

The usual advised dose of Myhep Lvir is one tablet should be administered as once a day. In HIV-1 co infected patients, Myhep Lvirdosage consideration is; Patient without cirrhosis: (adult or pediatric of 12 years of age or older with genotype I, IV, V or VI Chronic HCV) The prescribed dose of Myhep Lvir is one tablet should be taken orally as a single dose for 12 weeks

Genotype I

Without cirrhosis or compensated cirrhosis: Myhep Lvir should be taken alone as a single dose followed for 12 weeks
Therapy experienced without cirrhosis: Myhep Lvir should be taken as a single agent for once a day for 12 weeks

 Therapy experienced with compensated cirrhosis: Myhep Lvir tablet should be used for 24 weeks

In decompensated cirrhosis: Myhep Lvir should be combined with ribavirin to be used, followed for 12 weeks

Genotype I to IV

In liver transplantation patients with compensated cirrhosis or without cirrhosis: Myhep Lvir tablet should be combined with ribavirin for 12 weeks.
Genotype IV, V or VI :
Myhep Lvir tablets should be administered alone for 12 weeks for Without cirrhosis or with compensated cirrhosis patients: On the basis of body weight the dose of ribavirin should be calculated <75kg: 1000mg; ≥75kg: 1200mg Ribavirin should be administered with food.

 Mechanism of action :

Ledipasvir is a solid prohibitor of perpetual hepatitis C viral relating non structural 5A protein which is a viral phosphoprotein. The essential part of ledipasvir in hostile to viral action instrument; Restraint of; Replication Virion assembly Secretion The mechanism of sofosbuvir associated with against viral movement is; Sofosbuvir is prohibitor of nucleotide analogue of hepatitis C viral disease identified with non basic 5B polymerase. This catalyst is in charge of interceding the HCV RNA duplication. The dynamic type of sofosbuvir is in triphosphate shape, which included diminishing the common cell uridine nucleotide and is coordinated by HCV RNA polymerase into the broadened RNA preliminary strand, which is closed in viral chain end.

 PHARMACOKINETICS

Peak plasma concentration of Myhep Lvir :
Sofosbuvir: 0.8 to 1 hour & GS331007: 3.5 to 4 hours; ledipasvir: 4 to 4.5 hours No effect produced, while Myhep Lvirshould be administered with or without food.
Plasma protein binding capacity of Myhep Lvir :
Sofosbuvir: 61 to 65% & GS-331007: minimal binding effect, ledipasvir: >99.8%
Metabolism of Myhep Lvir :
Sofosbuvir: hepatic metabolism with cathepsin A, or carboxyl esterase 1 & ledipasvir: mediated by CYP1A2, 2C8, 2C9, 2C19, 2D6 & 3A4.
Elimination of Myhep Lvir : Major route of elimination is through urine & feces. Ledipasvir through urine by 87%; sofosbuvir through urine by 80%, feces by 14% & exhaled air by 3.5%
  side effect : 

Elevation of bilirubin , lipase , creatine kinase Severe bradycardia HBV reactivation Chest pain Dizziness Trouble in breathing Fatigue Headache Nausea Diarrhea Insomnia



Additional Information:

  • Pay Mode Terms: T/T (Bank Transfer)
  • Port of Dispatch: Mumbai
  • Delivery Time: Immediate

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Ledipasvir Medicines

Ledipasvir Medicines

Rs 12,500  / BottleGet Best Price

Minimum Order Quantity: 1 Bottle

Dose/Strength (ex. 1 mg or 1 ml)Ledipasvir 90mg & Sofosbuvir 400mg
Dosage FormTablet
Packaging TypeBottle
CompositionSofosbuvir 400mg & Ledipasvir 90mg
IndicationsHepatitis C
Packaging Size1x28
BrandStrides
ApplicationHepatitis C
We are manufacturer,trader & supplier of  Virpas Tablets. 
Specifications:
  • Item Code: 89736982
  • Virpas (Ledipasvir Sofosbuvir)
  • Brand name: Virpas
  • Active Ingredients(Generic Name): Ledipasvir Sofosbuvir
  • Company Name: Strides
  • Package: 28 tablets/bottle
  • Strength: Ledipasvir 90mg Sofosbuvir 400mg

 

Indication:

  • Treating chronic hepatitis C virus (HCV) infection in certain patients.
  • Ledipasvir Sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents. It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Daclatasvir 60mg is used with another antiviral medication (sofosbuvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Daclatasvir 60mg tablet should never be used without sofosbuvir. Daclatasvir  and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer.Daclatasvir Price, Daclatasvir Cost.Daclatasvir Dose.

Mechanism of action:

  • Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion. Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerasethe key enzyme mediating HCV RNA replication. The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.

 

 

Dosage and Administration:

  • Ledipasvir Sofosbuvir (90 mg/400 mg) is a fixed-dose combination tablet . The recommended dosage is one tablet once daily, with or without food.

 

Side effects:

  • Fatigue
  • nausea
  • Headache
  • Insomnia

 

Precaution:

  • Tell your doctor or dentist that you take Ledipasvir Sofosbuvir before you receive any medical or dental care, emergency care, or surgery.
  • Do not share needles, injection supplies, or items like toothbrushes or razors. Talk with your health care provider about ways to prevent the spread of HCV to others.

 

Store:

  • Ledipasvir Sofosbuvir room temperature away from moisture and heat


Additional Information:

  • Pay Mode Terms: T/T (Bank Transfer)
  • Port of Dispatch: Mumbai
  • Delivery Time: Immediate

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  • Ledviclear Tablets
  • Ledviclear Tablets
Ledviclear Tablets

Ledviclear Tablets

Rs 5,000  / BottleGet Best Price

Minimum Order Quantity: 1 Bottle

Dosage FormTablet
CompositionSofosbuvir & Ledipasvir
Drug NameLedviclear
Active IngredientSofosbuvir & Ledipasvir
BrandAbbott
IndicationsHep C
Dose/Strength400mg & 100mg
Usage/ApplicationHep C

We are manfacturer,trader & supplier of Ledviclear tablet. Uses of Ledviclear Tablet

Ledviclear 90mg/400mg Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.

 

 

How Ledviclear Tablet works

 

Ledviclear 90mg/400mg Tablet is a combination of two antiviral medicines: Ledipasvir and Sofosbuvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.

 

How to use Ledviclear Tablet

 

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ledviclear 90mg/400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

 

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Hepcvir L Tablets

Hepcvir L Tablets

Rs 7,500  / TabletGet Best Price

Minimum Order Quantity: 1 Tablet

BrandHepcvir L
Packaging Size28 Tablets
Dosage FormTablet
Dose/Strength400mg & 90mg
UsageClinical, Hospital
Packaging TypeBottle
CompositionSofosuvir 400mg & Ledipasvir 90mg
IndicationsHepatitis C
ApplicationHepatitis C
We are manfacturer,trader & supplier of  Hepcvir L Tablets.
Indication:
  • Treating chronic hepatitis C virus (HCV) infection in certain patients.
  • Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents.
  • It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Sofosbuvir and Ledipasvir is a combination  and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Sofosbuvir & Ledipasvir tablets, may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir ledipasvir , ledipasvir and sofosbuvir , ledipasvir and sofosbuvir cost, ledipasvir & sofosbuvir tablets, sofosbuvir ledipasvir price.

Mechanism of action:

  • Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion.
  • Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication.
  • The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.


Additional Information:

  • Pay Mode Terms: T/T (Bank Transfer)
  • Port of Dispatch: Mumbai
  • Delivery Time: Immediate

View Complete details

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Leihep (Sofosbuvir 400mg & Ledispasvir 90mg- Zydus)

Leihep (Sofosbuvir 400mg & Ledispasvir 90mg- Zydus)

Rs 6,500  / BottleGet Best Price

Minimum Order Quantity: 1 Bottle

Strength400mg/90mg
TreatmentHepatitis C virus infection (HCV)
Prescription/Non prescriptionPrescription
ManufacturerZydus
FormTablet
Dosage FormTablet
UsageClinical, Hospital
Packaging TypeBottle
CompositionSofosbuvir 400mg & Ledipasvir 90mg
IndicationsHepatitis C
Packaging Size1x28
BrandLediHep
ApplicationHepatitis C
We are manufacturer,trader & supplier of Ledihep  tablet.
Ledihep  tablet contains Sofosbuvir 400mg & Ledispasvir 90mg its should be used for both adults & pediatric patients with the age of 12 years or older or weight of at least 35kg. Used for; Genotype I, 4, 5, or 6 with compensated cirrhosis or without cirrhosis Genotype 1 infection with compensated cirrhosis or without cirrhosis Liver transplantation condition, genotype 1 with decompensated cirrhosis by use of ribavirin Genotype 1 or 4 without cirrhosis or with compensated cirrhosis by use of ribavirin Pediatric patients, HCV infection related to genotype 1, 4, 5, or 6 without cirrhosis or with compensated cirrhosis.
DOSAGE

The usual advised dose of Ledifos is one tablet should be administered as once a day. In HIV-1 co infected patients, Ledihep dosage consideration is; Patient without cirrhosis: (adult or pediatric of 12 years of age or older with genotype I, IV, V or VI Chronic HCV) The prescribed dose of Ledihep is one tablet should be taken orally as a single dose for 12 weeks.

Genotype I

 

Without cirrhosis or compensated cirrhosis: Ledifos should be taken alone as a single dose followed for 12 weeks
Therapy experienced without cirrhosis: Ledifos should be taken as a single agent for once a day for 12 weeks
Therapy experienced with compensated cirrhosis: Ledihep tablet should be used for 24 weeks
In decompensated cirrhosis: Ledihep should be combined with ribavirin to be used, followed for 12 weeks

Genotype I to IV

 

In liver transplantation patients with compensated cirrhosis or without cirrhosis: Ledifos tablet should be combined with ribavirin for 12 weeks.
Genotype IV, V or VI :
Ledihep tablets should be administered alone for 12 weeks for Without cirrhosis or with compensated cirrhosis patients: On the basis of body weight the dose of ribavirin should be calculated <75kg: 1000mg; >=75kg: 1200mg Ribavirin should be administered with food. Ledihep should be administered with or without food.
SIDE EFFECTS 

Elevation of bilirubin Elevation of lipase Elevation of creatine kinase Severe bradycardia HBV reactivation Chest pain Dizziness Trouble in breathing Fatigue Headache Nausea Diarrhea Insomnia
Ledifos tablet Manufactured  by Natco pharma Ltd



Additional Information:

  • Pay Mode Terms: T/T (Bank Transfer)
  • Port of Dispatch: Mumbai
  • Production Capacity: Large
  • Delivery Time: Immediate
  • Packaging Details: 28 tablets in a bottle

View Complete details

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