Apple Pharmaceuticals

Hepcvel is Sofosbuvir 400mg & Velpatasvir 100mg is the fixed dose combination of these two most widely used anti-viral agents. Sofosbuvir & Velpatasvir are directly acting anti-viral agents which are involved in the treatment of chronic hepatitis C viral infection. Sofosbuvir is usually combined with other anti-viral agent for exhibiting the prominent effects. Hepcvel is the FDA approved product, which is used in chronic HCV condition. Hepcvel should be used in genotype I, II, III, IV, V or VI associated hepatitis C viral infections.
DOSAGE BEFORE THE TREATMENT

Examine the patients thoroughly, before initiating the treatment with HCV anti-viral agents. Care should be taken while using HCV medication in patients with HCV/HIV-1co infections, in this case HBV reactivation occurs. Hepcvel tablets are recommended for chronic condition of hepatitis C viral infection related to genotype 1, 2, 3, 4, 5 or 6. The dosing of Hepcvel; The usual recommended dose of Hepcvel is, one tablet should be administered orally as a single dose. Hepcvel tablet consist of 100mg of Velpatasvir & 400mg of Sofosbuvir
UNFAVORABLE EFFECTS

Serious bradycardia occurs due to concomitant use of Hepcvel with amiodarone. Insomnia Irritability Headache Fatigue Nausea Asthenia

Resof Total is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing the viral NS5A inhibitor velpatasvir and sofosbuvir,a nucleotide inhibitor of the viral RNA polymerase. It is the first treatment, that works for all genotypic, and is taken entirely by mouth. A single tablet regimen is used for adults with genotype 1-6 chronic hepatitis C virus (HCV) infection with pangenotypic activity.

This medication is a combination of sofosbuvir and velpatasvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. sofosbuvir velpatasvir, sofosbuvir and velpatasvir, velpatasvir sofosbuvir, sofosbuvir velpatasvir brand name, It may sometimes be used with another antiviral medication (ribavirin). These drugs velpatasvir genotype 3 work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir velpatasvir cost, sofosbuvir velpatasvir, sofosbuvir plus velpatasvir available velpatasvir india.

Additional Information:

• Port of Dispatch: Mumbai

Velakast tablet contains Sofosbuvir 400mg & Velpatasvir 100mg is the fixed dose combination of these two most widely used anti-viral agents. Sofosbuvir & Velpatasvir are directly acting anti-viral agents which are involved in the treatment of chronic hepatitis C viral infection. Sofosbuvir is usually combined with other anti-viral agent for exhibiting the prominent effects. is the fixed dose combination of these two most widely used anti-viral agents. Sofosbuvir & Velpatasvir are directly acting anti-viral agents which are involved in the treatment of chronic hepatitis C viral infection. Sofosbuvir is usually combined with other anti-viral agent for exhibiting the prominent effects. Velakast is the FDA approved product, which is used in chronic HCV condition. Velakast should be used in genotype I, II, III, IV, V or VI associated hepatitis C viral infections. is the FDA approved product, which is used in chronic HCV condition. Velakast should be used in genotype I, II, III, IV, V or VI associated hepatitis C viral infections.
DOSAGE BEFORE THE TREATMENT

Examine the patients thoroughly, before initiating the treatment with HCV anti-viral agents. Care should be taken while using HCV medication in patients with HCV/HIV-1co infections, in this case HBV reactivation occurs. Velakast tablets are recommended for chronic condition of hepatitis C viral infection related to genotype 1, 2, 3, 4, 5 or 6. The dosing of Velpanat; The usual recommended dose of Velakast  is, one tablet should be administered orally as a single dose. Velakast  tablet consist of 100mg of Velpatasvir & 400mg of Sofosbuvir

WORKS

 

Sofosbuvir is a NS5B protein inhibitor, protein is essential for viral production. Sofosbuvir is a prodrug form, which get converted into active uridine triphosphate form which is required for anti-viral activity. This dynamic active moiety is get inserted into HCV RNA with the help of NS5B polymerase and leads as chain eliminator. Velpatasvir is pharmacologically acts as NS5A inhibitor; this protein is required for HCV viral production. Velpatasvir is involved its action in viral production process.
VELAKAST UNFAVORABLE EFFECTS 

Serious bradycardia occurs due to concomitant use of Velakast with amiodarone. Insomnia Irritability Headache Fatigue Nausea Asthenia

LAB ABNORMALITIES

Lipase elevation Elevation of creatine kinase Elevation of bilirubin levels

POST MARKETING EFFECTS

Cardiac disorders Rashes Angioedema

Sovihep D sofosbuvir 400mg & daclatasvir 60mg tablets are hostile to viral medicine Sovihep D tablets are single measurements treatment, it is a doctor prescribed medication utilized by the patients just under the information of restorative expert who are all around rehearsed Daclatasvir isn't utilized alone, for better activity it ought to be joined with Sofosbuvir tablet. In some condition Sovihep D is joined with ribavirin, a hostile to viral pharmaceutical utilized as a part of decompensated (Child Pugh B or C) cirrhosis
PRESCRIBED FOR

The primary sign of Sovihep D is; This mix tablets are utilized to treat the constant hepatitis C viral disease caused by genotype I or III The significant restriction happened while utilizing Hepcinat Plus tablets are lessening of steady virological reaction rate in hepatitis C genotype I or III contaminated patients.

PHARMACOLOGY

The activity of Sovihep D tablets are occurred by involving in some mechanism;

SOFOSBUVIR

 

Sofosbuvir containing sofosbuvir has hostile to hepaciviral movement, which is specifically acting medication displays its activity by disallowing NS5B RNA dependent RNA polymerase protein; fundamental for hepatitis viral duplication. Sofosbuvir is processed to frame uridine triphosphate, a fundamental dynamic metabolite which uncovered a hostile to viral action. The mixture of this dynamic metabolite into hepatitis viral RNA with the assistance of NS5B polymerase and causes viral chain cessation

DACLATASVIR

 

Daclatasvir containing Daclatasvir removes hostile to viral action by restricting NS5A protein which is needful in viral generation and virion collection

Sofokast and dacikast is an anti-viral medication which is used for preventing the disease progression of hepatitis C viral infection by reduces the multiplication of virus in the body. 

Sovihep V 400mg/100mg Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.

 

 

How Sovihep V Tablet works

 

Sovihep V 400mg/100mg Tablet is a combination of two antiviral medicines: Sofosbuvir and Velpatasvir. They work by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time.

 

How to use Sovihep V Tablet

 

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sovihep V 400mg/100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Virso 400mg Sofosbuvir 400mg tablets  is used with other antiviral medications (such as ribavirin, peginterferon, daclatasvir) to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It works by reducing the amount of hepatitis C virus in your body, which may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir cost, Sofosbuvir price , Sofosbuvir Buy online. 

Indication of Virso 400mg : 

  It is used for the treatment of hepatitis Cvirus (HCV) infection..

• Sofosbuvir allows most patients to be treated successfully without the use of peginterferon,an injectable drug with severe side effects.
• That is a key component of older drug combinations for the treatment of HCV.Sofosbuvir is used for the treatment of chronic hepatitis C, genotypes 1, 2, 3, and 4, in combination with pegylated interferon and ribavirin, or with ribavirin alone.
• It is also used in combination with the viral NS5a inhibitor ledipasvir in an interferon-free combination for the treatment of genotype 1 hepatitis C infection.
• Sofosbuvir is also used in HCV patients with an HIV coinfection.
• The treatment is based on a number of clinical trials, for example the ELECTRON trial which showed that a dual interferon-free regimen of sofosbuvir plus ribavirin produced a 24-week post-treatment sustained virological response (SVR24) rate of 100% for previously untreated patients with HCV genotypes 2 or 3.

Mechanism of action of Virso 400mg

• Sofosbuvir contains oral nucleotide analog inhibitor of the hepatitis C virus (HCV) polymerase.
• The drug is a direct-acting antiviral agent and interferes straight with the HCV lifecycle, restraining the viral replication. It can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator.
• The drug is available for oral use in the form of 400mg tablets.

Dosage and Administration of Virso 400mg

• The recommended daily dose of Sofosbuvir is 400mg tablet to be taken once daily with or without food.
• Sofosbuvir should be used in combination with Ribavirin or in combination with Pegylated Interferon and Ribavirin for the treatment of CHC (Chronic Hepatitis C) in adults.
•  How to use Virso 400mg  Tablet

Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition and response to treatment.

This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time each day.

How to use Virso 400mg Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Virso 400 mg Tablet is to be taken with food.

 Side effects:

• Adverse events associated with the use of Sofosbuvir in combination with Ribavirin may include, but are not limited to, the followingo Fatigue , headacheAdverse events associated with the use of Sofosbuvir in combination with Peginterferon Alfa and Ribavirin may include, but are not limited to, the following:o fatigue,headache, nausea, insomnia, anemia

Virso 400mg is manufactured and Marketed by Strides Shasun Ltd

Additional Information:

• Port of Dispatch: Mumbai

Indication:

• Treating chronic hepatitis C virus (HCV) infection in certain patients.
• Ledipasvir and sofosbuvir is a combination of 2 hepatitis C virus (HCV) antiviral agents.
• It reduces the amount of HCV in the body by preventing the spread of the HCV within the body.

Sofosbuvir and Ledipasvir is a combination and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.Sofosbuvir & Ledipasvir tablets, may sometimes be used with another antiviral medication (ribavirin). These drugs work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir ledipasvir , ledipasvir and sofosbuvir , ledipasvir and sofosbuvir cost, ledipasvir & sofosbuvir tablets, sofosbuvir ledipasvir price.

Mechanism of action:

• Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion.
• Sofosbuvir is a nucleotide analog inhibitor of hepatitis C virus NS5B polymerase—the key enzyme mediating HCV RNA replication.
• The triphosphate form of sofosbuvir (GS-461203) mimics the natural cellular uridine nucleotide and is incorporated by the HCV RNA polymerase into the elongating RNA primer strand, resulting in viral chain termination.

Hepcinat Lp Manufactured & Marketed by Natco Pharma Ltd

Additional Information:

• Port of Dispatch: Mumbai

Velpanat is the fixed dose combination of these two most widely used anti-viral agents. Sofosbuvir & Velpatasvir are directly acting anti-viral agents which are involved in the treatment of chronic hepatitis C viral infection. Sofosbuvir is usually combined with other anti-viral agent for exhibiting the prominent effects. Velpanat is the FDA approved product, which is used in chronic HCV condition. Velpanat should be used in genotype I, II, III, IV, V or VI associated hepatitis C viral infections.

DOSAGE BEFORE THE TREATMENT

Examine the patients thoroughly, before initiating the treatment with HCV anti-viral agents. Care should be taken while using HCV medication in patients with HCV/HIV-1co infections, in this case HBV reactivation occurs. Velpanat tablets are recommended for chronic condition of hepatitis C viral infection related to genotype 1, 2, 3, 4, 5 or 6. The dosing of Velpanat; The usual recommended dose of Velpanat is, one tablet should be administered orally as a single dose. Velpanat tablet consist of 100mg of Velpatasvir & 400mg of Sofosbuvir

WORKS

 

Sofosbuvir is a NS5B protein inhibitor, protein is essential for viral production. Sofosbuvir is a prodrug form, which get converted into active uridine triphosphate form which is required for anti-viral activity. This dynamic active moiety is get inserted into HCV RNA with the help of NS5B polymerase and leads as chain eliminator. Velpatasvir is pharmacologically acts as NS5A inhibitor; this protein is required for HCV viral production. Velpatasvir is involved its action in viral production process.
UNFAVORABLE EFFECTS 

Serious bradycardia occurs due to concomitant use of Velpanat with amiodarone. Insomnia Irritability Headache Fatigue Nausea Asthenia

LAB ABNORMALITIES

Lipase elevation Elevation of creatine kinase Elevation of bilirubin levels

POST MARKETING EFFECTS

Cardiac disorders Rashes Angioedema

Velpanat Tablet Manufactured & Marketed By Natco Pharma Ltd

Natdac 60mg tablets. Hepcinat and natdac is an anti-viral medication which is used for preventing the disease progression of hepatitis C viral infection by reduces the multiplication of virus in the body.