Anti Cancer Medicines

Product Details:

We are famous in this domain for offering an extensive array of Xbira 250 mg Tablets to our esteemed clients. Offered product is a drug used in combination with prednisone in metastatic castration-resistant prostate cancer. In addition to this, the offered assortment is available in a safe packaging at very reasonable rates.

Features:

• Accurate formulation
• Long shelf life
• No side effects
• Highly pure

Compositions:

• Abiraterone Acetate 250 mg Tablets

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Uses of Citafine Injection 1.4gm

 

Citafine 1.4 gm Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer and ovarian cancer.

 

 

How Citafine Injection works

 

Citafine 1.4 gm Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

 

How to use Citafine Injection

 

Your doctor or nurse will give you this medicine. Kindly do not self administer.

 

 

Uses of Citafine Injection

 

Citafine 1 gm Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer and ovarian cancer.

 

 

How Citafine Injection works

 

Citafine 1 gm Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

 

 

How to use Citafine Injection

 

Your doctor or nurse will give you this medicine. Kindly do not self administer.

 

 

 

 

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Compositions:

• Tamoxifen Citrate Tablets I.P. 20mg Cytotam

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Specifications:

• Efavir (Efavirenz)
• Brand name: Efavir
• Active Ingeridents(Generic Name) : Efavirenz
• Company Name: Cipla

Indication:

• This drug is used with other HIV medications to help control HIV infection.
• It helps to decrease the amount of HIV in your body so your immune system can work better.
• This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Efavir (Efavirenz) belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

 

Mechanism of action:

• Efavir (Efavirenz) falls in the NNRTI class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme which transcribes viral RNA into DNA.
• Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket.
• Efavir (Efavirenz) is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

 

Precaution:

• Before taking Efavir (Efavirenz), tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
• This product may contain inactive ingredients, which can cause allergic reactions or other problems.
• Talk to your pharmacist for more details.

 

Store:

• Store Efavir (Efavirenz) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C).
• Store in a tightly closed container away from heat, moisture, and light.

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Product Details:

Our respected clients can avail from us a quality proven a range of Alkeran 2mg Tablets, which is formulated by taking of optimum quality 2mg Melphalan BP. Melphalan is a bi functional alkylating agent that is active against selected human neoplastic diseases. Apart from this, this offered product is used in the treatment of ovarian cancers.

Features:

• Highly effective
• Precise composition
• No harmful chemical
• Safe to use

Compositions:

• Each Tablet Contains 2mg Melphalan BP

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Indication:

• It is used in the treatment of Acute Myelogenous Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL).
• It may be used in combination with other medicines.
• It may also be used for other conditions as determined by your doctor.

Mechanism of action:

• Daunotec (Daunorubicin) has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunotec (Daunorubicin) forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

Dosage Administration:

• Daunotec (Daunorubicin) is given by intravenous injection (IV).
• The syringe needle is placed directly into the tubing of a freely flowing IV solution into a vein or central line and the drug is given over several minutes.
• Daunotec (Daunorubicin) is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein.
• The nurse or doctor who gives this drug must be carefully trained.
• If you notice redness or swelling at the IV site while you are receiving Daunotec (Daunorubicin) , alert your health care professional immediately.
• The amount of Daunotec (Daunorubicin) you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have.
• Your doctor will determine your dose and schedule.

Side effects:

• All medicines may cause side effects, but many people have no, or minor, side effects.
• Check with your doctor if any of these most COMMON side effects persist or become bothersome:
• Diarrhea; hair loss; loss of appetite; mouth pain; nausea; sore throat; stomach pain; tiredness; weakness.

Precaution:

• Before starting Daunotec (Daunorubicin) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
• Do not take , products containing unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Daunotec (Daunorubicin) .
• You may be more sensitive to sunlight, take extra care to avoid sun exposure.
• People with congestive heart failure, those who have already had high doses of this drug or a similar drug, and those with permanent problems with blood counts (bone marrow suppression) cannot receive this drug.

 

Store:

• Daunotec (Daunorubicin) is usually handled and stored by a health care provider. If you are using Daunotec (Daunorubicin) at home, store Daunotec (Daunorubicin) as directed by your pharmacist or health care provider. Keep Daunotec (Daunorubicin) out of the reach of children and away from pets.

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Additional Information:

• Item Code: 84217181

Product Details:

We are providing an excellent quality array of Alphalan Tablets 2mg and 5mg to our prestigious clients. Our offered range of this tablet is prepared with the advanced technology and different chemical according to the market norms. Along with that, this is used in multiple myelomas, breast carcinoma, advanced ovarian carcinoma, polycythemia Vera, melanoma, and soft tissue sarcoma.

Features:

• Longer shelf life
• Easy to use
• High effectiveness
• Quick result

Compositions:

• Melphalan Tablets IP Alphalan 5 mg And 2 mg

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To fulfill the increasing demands of clients, we are highly engaged in offering Cytarabine Injection in the market. This is an anti-cancer medication and used to treat various types of leukemia, including acute and chronic myelogenous and acute lymphocytic leukemia. These offered ranges are also used to treat lymphoma, meningeal leukemia, and lymphoma.

Features:

• Long shelf life
• Accurate processing
• No harmful chemical
• Highly effective

Compositions:

• Cytarabine Injection 100mg/ml

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Product Details:

Since our establishment, we are instrumental in providing a quality assured grade of Geftinat Tablets. These tablets are formulated by utilizing top class chemical compounds with the help of progressive processing techniques by our adroit crew of professionals. As per the vivid needs of clients, we provide these tablets in various packaging options. The provided tablets are mainly used for the treatment of lung and prostate cancer

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Generic for Eloxatin (Oxaliplatin) is an anti-cancer chemotherapy injection used to treat advanced cancer Generic for Eloxatin (Oxaliplatin) is an anti-cancer chemotherapy injection used to treat advanced cancer of the colon or rectum (metastatic colorectal cancer). Oxaliplatin is used in combination with other anti-cancer drugs. This drug works by stopping the multiplication of the cancer cells. This medicine may also be used to treat other conditions as determined by your doctor. What is the recommended dosage of Generic for Eloxatin?

The dosage of Generic for Eloxatin prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label. What if you miss a dGeneric for Eloxatin (Oxaliplatin) is an anti-cancer chemotherapy injection used to treat advanced cancer of the colon or rectum (metastatic colorectal cancer). Oxaliplatin is used in combination with other anti-cancer drugs. This drug works by stopping the multiplication of the cancer cells. This medicine may also be used to treat other conditions as determined by your doctor. What is the recommended dosage of Generic for Eloxatin?

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• Item Code: 65371846

Product Details:

Leucovorin Calcium is used to prevent harmful effects of certain drugs (folic acid antagonists) such as methotrexate, trimethoprim, and pyrimethamine. It belongs to a class of medications called folic acid analogs. This medicine reduces the folic-acid-lowering side effects of methotrexate or similar medications by protecting healthy cells from their effects. It is also used to treat a condition known as megaloblastic anemia. This drug is used in combination with fluorouracil to treat cancer of the colon as well. This medicine may also be used to treat other conditions as determined by your doctor.What is the recommended dosage of Leucovorin Calcium?
The dosage of Leucovorin Calcium prescribed to each patient will vary. Always follow your physician’s instructions and/or the directions on the prescription drug label.Leucovorin Calcium can be taken with or without food.What if you miss a dose of Leucovorin Calcium?
If your physician has instructed or directed you to take Leucovorin Calcium medication in a regular schedule and you have missed a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, then skip the missed dose and go back to your regular dosing schedule. Do not double the doses unless otherwise directed.What if you overdose on Leucovorin Calcium?
Any medication taken in excess can have serious consequences. If you suspect an overdose of Leucovorin Calcium, seek medical attention immediately

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• Item Code: 65371871

Product Details:

Cytarabine Injection is an Anti-Cancer Medication and used to treat different forms of leukemia, including acute and chronic myelogenous (AML and CML) and acute lymphocytic leukemia (ALL). Cytarabine, which is also called Ara C or cytosine arabinoside. Biobin Injection manufactured by Biochem. This medicine is also used to treat lymphoma, meningeal leukemia and lymphoma (cancers found in the lining of the brain and spinal cord).

Other Brands:

• Cytosar-U, Tarabine PFS (Pfizer), Depocyt,AraC
• Cytarabine is an antineoplastic.
• It works by disrupting the growth of cancer cells.
• Cytarabine is a chemotherapy drug used to treat various types of cancer.
• This injection medication belongs to the group of medicines called antineoplastics. Cytarabine works by slowing or stopping the growth of cancer cells.
• This drug is used alone or in combination with other medications.

• As an injection into the layer of tissue between the skin and the muscle (subcutaneous or SubQ).
• As an injection into the muscle (intramuscular or IM).
• Another method it is given is by intraventricular or intrathecal infusion.
• This method is used when drugs need to reach the cerebrospinal fluid (CSF) the fluid that is surrounding the brain and spinal cord, the drug is infused directly into the spinal fluid.
• There is no pill form of cytarabine.
• The amount of cytarabine that you receive and the way it is given depends on many factors, including the type of cancer you have, your height and weight, your general health, any other health problems you may have. Your doctor will determine your dose, how it should be given and the schedule.

 

Other Details:

• Do not receive any kind of immunization or vaccination without your doctor's approval while taking cytarabine.
• Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment.
• Pregnancy category D (cytarabine may be hazardous to the fetus.
• Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).
• For both men and women: Do not conceive a child (get pregnant) while taking cytarabine.
• Barrier methods of contraception, such as , are recommended.
• Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.
• Do not breast feed while taking this medication.
• All medicines may cause side effects, but many people have no, or minor, side effects.
• Check with your doctor if any of these most COMMON side effects persist or become bothersome:
  Diarrhea; dizziness; hair loss; loss of appetite; nausea; tiredness; vomiting; weakness.
  Seek medical attention right away if any of these SEVERE side effects occur:
  Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding in the eye; bloody or black, tarry stools; chest pain;

Warning:

• This information should not be used to decide whether or not to take Cytarabine or any other medicine.
• Only your health care provider has the knowledge and training to decide which medicines are right for you.
• This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition.

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Product Details:

Rheumatrex (Methotrexate 7.5mg)

• Generic for Rheumatrex (Methotrexate) is used to treat certain types of cancer such as breast cancer, lung cancer, neck cancer, and skin cancer.
• Methotrexate is also used to treat severe psoriasis and rheumatoid arthritis. This medication works by interfering with the growth of certain cells of the body, as well as by suppressing the immune system.

Recommended Dosage - Discount Prescription Drug Generic for Rheumatrex

• The dosage of Generic for Rheumatrex prescribed to each patient will vary.
• Always follow your physician’s instructions and/or the directions on the prescription drug label.
• Drink plenty of fluids while taking Generic for Rheumatrex tablets.

Overdose of Generic for Rheumatrex:

• Any medication taken in excess can have serious consequences.
• If you suspect an overdose of Generic for Rheumatrex, seek medical attention immediately.

Side Effects of Generic for Rheumatrex:

• Like other medicines, Generic for Rheumatrex can cause some side effects.
• If they do occur, the side effects of Generic for Rheumatrex are most likely to be minor and temporary.
• However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.
• It is pertinent to note that side effects of Generic for Rheumatrex cannot be anticipated. If any side effects of Generic for Rheumatrex develop or change in intensity, the doctor should be informed as soon as possible.
• Generic for Rheumatrex can cause side effects such as nausea, vomiting, dizziness, headache, and blurred vision. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Generic for Rheumatrex.

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Indication:

• It is used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.
• Temoside (Temozolomide) is an antineoplastic agent.
• It works by stopping cancer cells from growing and reproducing.

 

Mechanism of action:

• The therapeutic benefit of Temoside (Temozolomide) depends on its ability toalkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions ofguanine residues.
• This methylation damages the DNA and triggers the death of tumor cells.
• However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of Temoside (Temozolomide) , by expressing a protein O⁶-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene.
• In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by Temoside (Temozolomide).
• Conversely, the presence of AGT protein in brain tumors predicts poor response to Temoside (Temozolomide) and these patients receive little benefit from chemotherapy with Temoside (Temozolomide). 

Dosage and Administration:

• This medication is given in a capsule form by mouth.
• Take on an empty stomach (1 hour before or 2 hours after meals or at bedtime) to reduce stomach upset.
• Do not open, crush, or chew capsules; swallow capsules whole with full 8 ounces of water.
• The frequency and the amount of this medication you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dosage and schedule.

Precaution:

• Before starting Temoside (Temozolomide) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
• Do not take , or products containing unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Temoside (Temozolomide) .
• Let your health care provider know if you've had an allergic reaction to this drug or dacarbazine (DTIC) in the past, you may not be able to take temozolamide.

 

Store:

• Temoside (Temozolomide) is usually handled and stored by a health care provider. If you are using Temoside (Temozolomide) at home, store Temoside (Temozolomide) as directed by your pharmacist or health care provider. Keep Temoside (Temozolomide) out of the reach of children and away from pets.

 

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Additional Information:

• Item Code: 84261633

Product Details:

Our organization set a unique position in the market by providing a wide gamut of Armotraz Tablet in the market. The offered quality approved collections of the product is indicated for the treatment of advanced cancer in postmenopausal women with disease progression following tamoxifen therapy. In addition to this, this is used to minimize the risk of cancer.

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Product Details:

We are the most significant firms, indulged in providing highly effective Sorafenat Tablets. This tablet is used for the treatment of kidney cancer. Formulated using the finest quality chemical compounds and contemporary techniques, this tablet is widely used in pharmaceutical field and industry. Moreover, our clients can avail this tablet at reasonable prices.

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Compositions:

• Clokeran (Chlorambucil) Tablets IP

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Item Code: 84261505

Temonat (Temozolomide) 

Brand name: Temonat

Active Ingeridents(Generic Name) : Temozolomide 

Company Name: Natco

Package: 5 Capsules

Strength: 250mg

 

Indication:

 

It is used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.

Temonat (Temozolomide) is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.

 

Mechanism of action:

The therapeutic benefit of Temonat (Temozolomide) depends on its ability toalkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions ofguanine residues. This methylation damages the DNA and triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of Temonat (Temozolomide) , by expressing a protein O⁶-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene.In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by Temonat (Temozolomide) .Conversely, the presence of AGT protein in brain tumors predicts poor response to Temonat (Temozolomide) and these patients receive little benefit from chemotherapy with Temonat (Temozolomide) . 

 

 

Dosage and Administration:

• This medication is given in a capsule form by mouth.
• Take on an empty stomach (1 hour before or 2 hours after meals or at bedtime) to reduce stomach upset.
• Do not open, crush, or chew capsules; swallow capsules whole with full 8 ounces of water.
• The frequency and the amount of this medication you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dosage and schedule.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

 

Anxiety; back pain; breast pain; constipation; cough; diarrhea; dizziness; drowsiness; dry skin; hair loss; headache; joint pain; loss of appetite; mild stomach pain; mouth or tongue sores; muscle aches; nausea; taste changes; tiredness; trouble sleeping; vomiting; weakness; weight gain.

 

Precaution:

 

• Before starting Temonat (Temozolomide) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take , or products containing aspirin unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Temonat (Temozolomide) .
• Let your health care provider know if you've had an allergic reaction to this drug or dacarbazine (DTIC) in the past, you may not be able to take temozolamide.

 

Store: Temonat (Temozolomide) is usually handled and stored by a health care provider. If you are using Temonat (Temozolomide) at home, store Temonat (Temozolomide) as directed by your pharmacist or health care provider. Keep Temonat (Temozolomide) out of the reach of children and away from pets.

 

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PRODUCT DESCRIPTIONItem Code: 84261438

Temonat (Temozolomide) 

Brand name: Temonat

Active Ingeridents(Generic Name) : Temozolomide 

Company Name: Natco

Package: 5 Capsules

Strength: 100mg

 

Indication:

 

It is used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.

Temonat (Temozolomide) is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.

 

Mechanism of action:

The therapeutic benefit of Temonat (Temozolomide) depends on its ability toalkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions ofguanine residues. This methylation damages the DNA and triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of Temonat (Temozolomide) , by expressing a protein O⁶-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene.In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by Temonat (Temozolomide) .Conversely, the presence of AGT protein in brain tumors predicts poor response to Temonat (Temozolomide) and these patients receive little benefit from chemotherapy with Temonat (Temozolomide) . 

 

 

Dosage and Administration:

• This medication is given in a capsule form by mouth.
• Take on an empty stomach (1 hour before or 2 hours after meals or at bedtime) to reduce stomach upset.
• Do not open, crush, or chew capsules; swallow capsules whole with full 8 ounces of water.
• The frequency and the amount of this medication you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dosage and schedule.

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

 

Anxiety; back pain; breast pain; constipation; cough; diarrhea; dizziness; drowsiness; dry skin; hair loss; headache; joint pain; loss of appetite; mild stomach pain; mouth or tongue sores; muscle aches; nausea; taste changes; tiredness; trouble sleeping; vomiting; weakness; weight gain.

 

Precaution:

 

• Before starting Temonat (Temozolomide) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Temonat (Temozolomide) .
• Let your health care provider know if you've had an allergic reaction to this drug or dacarbazine (DTIC) in the past, you may not be able to take temozolamide.

 

Store: Temonat (Temozolomide) is usually handled and stored by a health care provider. If you are using Temonat (Temozolomide) at home, store Temonat (Temozolomide) as directed by your pharmacist or health care provider. Keep Temonat (Temozolomide) out of the reach of children and away from pets.

 

Quantity : 1 Bottle

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PRODUCT DESCRIPTION
Item Code: 65369105Since our establishment, we are engaged in offering an excellent quality Temodal Capsule. The offered medicine is used for the treatment of brain tumors. The offered medicine is formulated at our latest processing set up by our skilled professionals with the aid of cutting-edge processing technology using the best grade chemical compounds. Also, we offer this medicine in diverse packaging options.
Features:

• Instant relief
• Unadulterated
• Long shelf life

Quantity : 5 Strip

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PRODUCT DESCRIPTIONItem Code: 82875736Bortenat (Bortezomib)

Brand name: Bortenat

Active Ingeridents(Generic Name) : Bortezomib

Company Name: Natco Pharma

Package: 1 vial

Strength : 2mg

Indication:

It is the first therapeutic proteasome inhibitor to be tested in humans. Proteasomes are cellular complexes that break down proteins. In some cancers, the proteins that normally kill cancer cells are broken down too quickly. Bortezomib interrupts this process and lets those proteins kill the cancer cells. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.

Mechanism of action:

The boron atom in bortezomib binds the catalytic site of the 26S proteasome^] with high affinity and specificity. In normal cells, the proteasome regulates protein expression and function by degradation of ubiquitylated proteins, and also cleanses the cell of abnormal or misfolded proteins. Clinical and preclinical data support a role in maintaining the immortal phenotype of myeloma cells, and cell-culture and xenograft data support a similar function in solid tumor cancers.

Dosage and Administration:

Use bortezomib as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Drinking extra fluids while you are taking bortezomib is recommended. Check with your doctor for instructions.

· Bortezomib is given as an injection into a vein or under the skin at your doctor's office, hospital, or clinic. Bortezomib is not intended to be injected into the spinal cord. Contact your health care provider if you have any questions.

· It is very important that each dose is given at the scheduled time. If you miss a dose of bortezomib, contact your doctor right away to establish a new dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use bortezomib.

 

Side effects:

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; headache; loss of appetite; mild stomach pain; nausea; stomach upset; taste changes; tiredness; trouble sleeping; vomiting; weakness.

Precaution:

· Bortezomib may cause dizziness, fatigue, fainting, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use bortezomib with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

· Bortezomib may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Store:

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.Keep out of the reach of children.Do not keep outdated medicine or medicine no longer needed.

Quantity : 1 Piece

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Item Code: 82875833Bortecad (Bortezomib Inj)

Brand name: Bortecad

Active Ingeridents(Generic Name) : Bortezomib Inj

Company Name: Cadila

Package: 1 vial

Strength : 2mg

Indication:

It is the first therapeutic proteasome inhibitor to be tested in humans. Proteasomes are cellular complexes that break down proteins. In some cancers, the proteins that normally kill cancer cells are broken down too quickly. Bortezomib interrupts this process and lets those proteins kill the cancer cells. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.

Mechanism of action:

The boron atom in bortezomib binds the catalytic site of the 26S proteasome^] with high affinity and specificity. In normal cells, the proteasome regulates protein expression and function by degradation of ubiquitylated proteins, and also cleanses the cell of abnormal or misfolded proteins. Clinical and preclinical data support a role in maintaining the immortal phenotype of myeloma cells, and cell-culture and xenograft data support a similar function in solid tumor cancers.

Dosage and Administration:

Use bortezomib as directed by your doctor. Check the label on the medicine for exact dosing instructions.

· Drinking extra fluids while you are taking bortezomib is recommended. Check with your doctor for instructions.

· Bortezomib is given as an injection into a vein or under the skin at your doctor's office, hospital, or clinic. Bortezomib is not intended to be injected into the spinal cord. Contact your health care provider if you have any questions.

· It is very important that each dose is given at the scheduled time. If you miss a dose of bortezomib, contact your doctor right away to establish a new dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use bortezomib.

 

Side effects:

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; headache; loss of appetite; mild stomach pain; nausea; stomach upset; taste changes; tiredness; trouble sleeping; vomiting; weakness.

Precaution:

· Bortezomib may cause dizziness, fatigue, fainting, or vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use bortezomib with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

· Bortezomib may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Store:

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.Keep out of the reach of children.Do not keep outdated medicine or medicine no longer needed.

Quantity : 1 Piece

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Our respected clients can avail from us a quality proven range of Pemnat Pemetrexed Injection. This offered range is used to treat two types of lung cancers like non-small cell lung cancer and mesothelioma which is rare cancer associated with asbestos exposure. This cancer medication works by slowing the spread and growth of cancer cells in the body.

Features:

• Highly effective
• Long shelf life
• Precise composition
• Safe to use

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PRODUCT DESCRIPTIONItem Code: 84200214

Votrient (Pazopanib)

Brand name: Votrient

Active Ingeridents (Generic Name) : Pazopanib Hcl

Company Name: Glaxosmithkline

Package: 30 tablets

Strength : 400mg

Indication:

Treating patients with advanced kidney cancer. It is also used to treat patients with certain types of advanced soft tissue cancer who have received chemotherapy in the past. It may also be used for other conditions as determined by your doctor. Votrient (Pazopanib) is a tyrosine kinase inhibitor. It works by preventing the growth of cancer cells.

Mechanism of action:

Votrient (Pazopanib) is a second-generation multitargeted tyrosine kinase inhibitor against vascular endothelial growth factor receptor-1, -2, and -3, platelet-derived growth factor receptor-alpha, platelet-derived growth factor receptor-beta, and c-kit. These receptor targets are part of the angiogenesis pathway that facilitates the formation of tumour blood vessel for tumour survival and growth.

Dosage and Administration:

Use Votrient (Pazopanib) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

 

· Votrient (Pazopanib) comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Votrient (Pazopanib) refilled.

· Take Votrient (Pazopanib) by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

· Swallow Votrient (Pazopanib) whole. Do not break, crush, or chew before swallowing.

· Do not eat grapefruit or drink grapefruit juice while you use Votrient (Pazopanib).

· If you miss a dose of Votrient (Pazopanib), take it as soon as possible. If there are less than 12 hours before your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Votrient (Pazopanib).

Side effects:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dry skin; hair loss; headache; indigestion; lightening of hair or skin color; loss of appetite; mild stomach pain; muscle or bone pain; nausea; taste changes; tiredness; trouble sleeping; tumor pain; vomiting; weakness; weight loss.

Precaution:

• Before starting Votrient (Pazopanib) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). While taking Votrient (Pazopanib), ask your doctor before you take or products containing .
• While taking Votrient (Pazopanib), do not receive any kind of immunization or vaccination without your doctor’s approval.

Store:

Store Votrient (Pazopanib) between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Votrient (Pazopanib) out of the reach of children and away from pets.

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Indication:

• indicated for organ transplant rejection prophylaxis. Patients are prescribed this medicine after an organ transplant, so as to help prevent the immune system from attacking the organ and to stop the body rejecting the transplant.

Mechanism of action:

• Tacrolimus is a macrolide calcineurin inhibitor.
• In T-cells, activation of the T-cell receptor normally increases intracellular calcium, which acts via calmodulin to activate calcineurin.
• Calcineurin then dephosphorylates the transcription factor nuclear factor of activated T-cells (NF-AT), which moves to the nucleus of the T-cell and increases the activity of genes coding for IL-2 and related cytokines. Tacrolimus prevents the dephosphorylation of NF-AT.
• In detail, Tacrolimus reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex.
• This FKBP12-FK506 complex interacts with and inhibits calcineurin, thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.
• Although this activity is similar to that of ciclosporin, the incidence of acute rejection is reduced by tacrolimus use over ciclosporin.
• Although short-term immunosuppression concerning patient and graft survival is found to be similar between the two drugs, tacrolimus results in a more favorable lipid profile, and this may have important long-term implications given the prognostic influence of rejection on graft survival. 

 

Dosage and Administration:

• Oral tacrolimus is taken twice daily. Starting doses range between 0.075 mg/kg/day to 0.2 mg/kg/day. Doses vary widely and are based on tests that measure the amount of tacrolimus in the blood. Taking tacrolimus with food can reduce some of the abdominal pain that can occur with this medicine; however, food can reduce the amount of tacrolimus that is absorbed. This is especially true with fatty foods. Capsules should be taken consistently with or without food in order to avoid major swings in blood levels. Grapefruit juice increases blood levels of tacrolimus and should be avoided. The injection is only used for patients who cannot tolerate tacrolimus capsules. 

 

Precaution:

• An overdose Tacrolimus Unlikely to threaten life, call an emergency room or a poison control center for advice if you suspect that a very large dose of Tacrolimus has been ingested.
• There are no restrictions on food, beverages, or activities while taking Tacrolimus otherwise directed by your physician. 

Store:

• Tacrolimus is usually handled and stored by a health care provider. If you are using tacrolimus at home, store tacrolimus as directed by your pharmacist or health care provider. Keep tacrolimus out of the reach of children and away from pets.

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• Item Code: 82869272

Product Details:

Indication:

• It is used in the treatment of various cancers, among them malignant melanoma, Hodgkin's lymphoma, sarcoma, and islet cell carcinoma of the pancreas.
• Dacarbazine is a member of the class of alkylating agents, which destroy cancer cells by adding an alkyl group (C_nH_2n+1) to its DNA.
• Dacarbazine is normally administered by intravenous infusion (IV) under the immediate supervision of a doctor or nurse. Dacarbazine is bioactivated in liver by demethylation to "MTIC" and then to diazomethane, which is an alkylating agent.
• dacarbazine is commonly used as a single agent in the treatment of metastatic melanoma, and as part of the ABVDchemotherapy regimen to treat Hodgkin's lymphoma, and in the MAID regimen for sarcoma.
• Dacarbazine was proven to be just as efficacious as procarbazine in the German trial for paediatric Hodgkin's lymphoma, without the teratogenic effects.
• Thus COPDAC has replaced the former COPP regime in children for TG2 3 following OEPA.

Precaution:

• It is recommended that dacarbazine should only be administered under the supervision of a physician specialised in oncology, having the facilities for regular monitoring of clinical, biochemical and haematological effects, during and after therapy.
• If symptoms of a liver or kidney functional disorder or symptoms of a hypersensitivity reaction are observed immediate cessation of therapy is required.
• If veno-occlusive disease of the liver occurs, further therapy with dacarbazine is contra-indicated.
• Dacarbazine should be handled according to standard procedures for cytostatics that have mutagenic, carcinogenic and teratogenic effects.

 

Store:

• Store medicines at room temperature, away from heat and direct light.
• Do not freeze medicines unless the packaging or storage instructions clearly require you to do that.
• Keep medicines away from children and pets to prevent them from accidental consumption.

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Additional Information:

• Item Code: 82873598

Product Details:

Pirfenex (Pirfenidone) is an anti-fibrotic medicine indicated for the treatment of the lung disease IPF (idiopathic pulmonary fibrosis). It is believed to work by decreasing fibroblast growth and slowing down disease progression. Pirfenex (Pirfenidone) is an anti-fibrotic medicine indicated for the treatment of the lung disease IPF (idiopathic pulmonary fibrosis). It is believed to work by decreasing fibroblast growth and slowing down disease progression. IPF is a progressive disease in which the formation of scar tissue occurs in the lungs. This scar tissue gets thicker as the disease progresses, which causes stiff lungs. As a result of this, lung function is reduced and it is more difficult for oxygen to get from the lungs to the blood and vital organs. Breathing difficulties could also occur. This medicine may affect TGF (transmforming growth factor) and TNF (tumor necrosis factor) production, which can result in reduced inflammation and disruption of fibrosis. Although treatment will not cure the condition, it is used to help slow down the advancement of the disease. Pirfenex (Pirfenidone) comes in the form of 200mg strength tablets for oral administration. Patients are often told to take the medicine alongside food, so as to reduce the occurrence of vertigo or sickness. Physicians may direct patients to take it 3 times per day, however changes to the dosage schedule may be ordered by the physician, especially during the first 15 days after treatment commences. Regular medical appointments will be required so that your physician can monitor your progress and to ensure that it is not causing any harmful side effects to the liver. Make sure that you attend every scheduled check-up, and ensure that you comply with all instructions provided by the physician. Treatment of IPF or any other conditions with Pirfenex (Pirfenidone) may cause side effects. Report all reactions to your physician. Possible side effects include

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Additional Information:

• Item Code: 64728112

Product Details:

Specifications:

• Brand Name: Honvan 120mg Tablet
• Generic Name: Fosfestrol tetrasodium 120mg
• Contents: Fosfestrol tetrasodium 120mg
• Form: Tablets
• Manufacturer Zydus Biogen ( Baxter)

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Additional Information:

• Item Code: 65461398

Product Details:

Specifications:

• Brand name: Myezom
• Active Ingeridents(Generic Name) : Bortezomib
• Company Name: Dr.Reddy’s
• Package: 1 vial

Indication:

• Myezom (Bortezomib) is used to treat multiple myeloma and mantle cell lymphoma.
• Myezom (Bortezomib) is sometimes given after other cancer medications have been tried without successful treatment.

Mechanism of action:

• Myezom (Bortezomib) is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in mammalian cells.
• The 26S proteasome is a large protein complex that degrades ubiquitinated proteins.
• The active site of the proteasome has chymotrypsin-like, trypsin-like, and postglutamyl peptide hydrolysis activity. The 26S proteasome degrades various proteins critical to cancer cell survival, such as cyclins, tumor suppressors, BCL-2, and cyclin-dependent kinase inhibitors.
• Inhibition of these degradations sensitizes cells to apoptosis. Myezom (Bortezomib) is a potent inhibitor of 26S proteasome, which sensitizes activity in dividing multiple myeloma and leukemic cells, thus inducing apoptosis.

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Additional Information:

• Item Code: 84199968

Product Details:

Specifications:

• Daunorubitec (Daunorubicin)
• Brand name: Daunorubitec
• Active Ingeridents (Generic Name) : Daunorubicin
• Company Name: United Biotech
• Package: Vial

 

Indication:

• It is used in the treatment of Acute Myelogenous Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL).
• It may be used in combination with other medicines.
• It may also be used for other conditions as determined by your doctor.

Mechanism of action:

• Daunorubitec (Daunorubicin) has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunorubitec (Daunorubicin) forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

Dosage Administration:

• Daunorubitec (Daunorubicin) is given by intravenous injection (IV). The syringe needle is placed directly into the tubing of a freely flowing IV solution into a vein or central line and the drug is given over several minutes.
• Daunorubitec (Daunorubicin) is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein.
• The nurse or doctor who gives this drug must be carefully trained.
• If you notice redness or swelling at the IV site while you are receiving Daunorubitec (Daunorubicin) , alert your health care professional immediately.
• The amount of Daunorubitec (Daunorubicin) you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have. Your doctor will determine your dose and schedule.

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Specifications:

• Cerubidine (Daunorubicin)
• Brand name: Cerubudine
• Active Ingeridents (Generic Name) : Daunorubicin
• Company Name: Erfa
• Package: Vial

 

Indication:

• It is used in the treatment of Acute Myelogenous Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL).
• It may be used in combination with other medicines.
• It may also be used for other conditions as determined by your doctor.

Mechanism of action:

• Cerubidine (Daunorubicin) has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Cerubidine (Daunorubicin) forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.

Dosage Administration:

• Cerubidine (Daunorubicin) is given by intravenous injection (IV). The syringe needle is placed directly into the tubing of a freely flowing IV solution into a vein or central line and the drug is given over several minutes.
• Cerubidine (Daunorubicin) is a vesicant. A vesicant is a chemical that causes extensive tissue damage and blistering if it escapes from the vein.
• The nurse or doctor who gives this drug must be carefully trained.
• If you notice redness or swelling at the IV site while you are receiving Cerubidine (Daunorubicin) , alert your health care professional immediately.
• There is no pill form of Cerubidine (Daunorubicin) .
• The amount of Cerubidine (Daunorubicin) you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer you have.
• Your doctor will determine your dose and schedule.

 

Side effects:

• All medicines may cause side effects, but many people have no, or minor, side effects.
• Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Precaution:

• Before starting Cerubidine (Daunorubicin) treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
• Do not take , products containing unless your doctor specifically permits this.
• Do not receive any kind of immunization or vaccination without your doctor's approval while taking Cerubidine (Daunorubicin) .
• You may be more sensitive to sunlight, take extra care to avoid sun exposure.
• People with congestive heart failure, those who have already had high doses of this drug or a similar drug, and those with permanent problems with blood counts (bone marrow suppression) cannot receive this drug.

 

Store:

• Cerubidine (Daunorubicin) is usually handled and stored by a health care provider.
• If you are using Cerubidine (Daunorubicin) at home, store Cerubidine (Daunorubicin) as directed by your pharmacist or health care provider.
• Keep Cerubidine (Daunorubicin) out of the reach of children and away from pets.

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Additional Information:

• Item Code: 84217335

Product Details:

Indication:

• Etanercept, an immunomodulating anti-TNF-alpha biologic, is indicated for the treatment of rheumatoid arthritis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis (PsA), ankylosing spondylitis (AS) and plaque psoriasis (PsO). Etanercept can be prescribed either as a monotherapy or as a combined therapy with methotrexate.

 

Dosage:

• For treatment of RA, AS and PsA patients (Adults):
• Consider administration of 50 mg of Etanercept, every week
• For treatment of PsO patients (Adults):
• Start with an initial dose of 50 mg twice weekly for three months. The maintenance dose can be 50 mg, once weekly.

 

Precautions:

• Etanercept is contraindicated in patients with serious and invasive fungal infections and tuberculosis and malignancies including lymphoma, melanoma and non-melanoma skin cancers. Caution should be exercised while prescribing Etanercept to heart patients, juvenile patients, atopic individuals and latent hepatitis B virus infected patients
• Major Side Effects
• You should check with your doctor immediately if any of these sideeffects occur when taking etanercept:

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