Andheri East, Mumbai, Maharashtra
GST No. 27AGUPM2690J1ZO
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Minimum Order Quantity: 1 Bottle
Brand | Temonat |
Composition | Temozolamide |
Manufacturer | Natco |
Treatment | Cancer |
Prescription/Non prescription | Prescription |
Packaging Size | 5Capsule/Bottle |
Dose/Strength | 100mg |
Temonat (Temozolomide)
Brand name: Temonat
Active Ingeridents(Generic Name) : Temozolomide
Company Name: Natco
Package: 5 Capsules
Strength: 100mg
Indication:
It is used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.
Temonat (Temozolomide) is an antineoplastic agent. It works by stopping cancer cells from growing and reproducing.
Mechanism of action:
The therapeutic benefit of Temonat (Temozolomide) depends on its ability toalkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions ofguanine residues. This methylation damages the DNA and triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of Temonat (Temozolomide) , by expressing a protein O6-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene.In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by Temonat (Temozolomide) .Conversely, the presence of AGT protein in brain tumors predicts poor response to Temonat (Temozolomide) and these patients receive little benefit from chemotherapy with Temonat (Temozolomide).
Dosage and Administration:
Side effects:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Anxiety; back pain; breast pain; constipation; cough; diarrhea; dizziness; drowsiness; dry skin; hair loss; headache; joint pain; loss of appetite; mild stomach pain; mouth or tongue sores; muscle aches; nausea; taste changes; tiredness; trouble sleeping; vomiting; weakness; weight gain.
Precaution:
Store: Temonat (Temozolomide) is usually handled and stored by a health care provider. If you are using Temonat (Temozolomide) at home, store Temonat (Temozolomide) as directed by your pharmacist or health care provider. Keep Temonat (Temozolomide) out of the reach of children and away from pets.
Quantity : 1 Bottle
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Minimum Order Quantity: 1 Strip
Medicine Type | Allopathic |
Gender | Unisex |
Dosage Form | Tablets |
Power (Mg) | 400 mg |
Grade standard | Medicine Grade |
Packaging Type | Strips |
Nausea, Headache, Vomiting, Rash, Dyspepsia, Abdominal pain, Constipation, Itching, Increased liver enzymes, Abdominal distension, Diarrhoea.
How to use Desifer Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Desifer 400mg Tablet is to be taken empty stomach.View Complete details
Minimum Order Quantity: 1 Piece
Packaging Size | 5 x 10 Tablets |
Dose/Strength (ex. 1 mg or 1 ml) | 125 mg |
Usage | Clinical, Hospital |
Additional Information:
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Minimum Order Quantity: 3 Bottle
Brand | Hetero |
Treatment | multiple myeloma |
Country of Origin | Made in India |
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Minimum Order Quantity: 3 Bottle
Brand | Hetero |
Treatment | multiple myeloma |
Country of Origin | Made in India |
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Minimum Order Quantity: 3 Bottle
Brand | Hetero |
Treatment | multiple myeloma |
Country of Origin | Made in India |
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Usage | Hospital, Clinical |
Dose | 2mg, 5mg |
Packaging Size | 25 Tablets |
Brand | Natco |
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