Apple Pharmaceuticals

We are manfacturer,trader & supplier of Velpaclear tablet. This medication is a combination of sofosbuvir and velpatasvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. sofosbuvir velpatasvir, sofosbuvir and velpatasvir, velpatasvir sofosbuvir, sofosbuvir velpatasvir brand name, It may sometimes be used with another antiviral medication (ribavirin). These drugs velpatasvir genotype 3 work by reducing the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover. Chronic hepatitis C infection can cause serious liver problems such as scarring (cirrhosis), or liver cancer. sofosbuvir velpatasvir cost, sofosbuvir velpatasvir, sofosbuvir plus velpatasvir available velpatasvir india.

Examine the patients thoroughly, before initiating the treatment with HCV anti-viral agents. Care should be taken while using HCV medication in patients with HCV/HIV-1co infections, in this case HBV reactivation occurs. Hepcvel tablets are recommended for chronic condition of hepatitis C viral infection related to genotype 1, 2, 3, 4, 5 or 6. The dosing of Hepcvel; The usual recommended dose of Hepcvel is, one tablet should be administered orally as a single dose. Hepcvel tablet consist of 100mg of Velpatasvir & 400mg of Sofosbuvir
UNFAVORABLE EFFECTS

Serious bradycardia occurs due to concomitant use of Hepcvel with amiodarone. Insomnia Irritability Headache Fatigue Nausea Asthenia

Examine the patients thoroughly, before initiating the treatment with HCV anti-viral agents. Care should be taken while using HCV medication in patients with HCV/HIV-1co infections, in this case HBV reactivation occurs. Velakast tablets are recommended for chronic condition of hepatitis C viral infection related to genotype 1, 2, 3, 4, 5 or 6. The dosing of Velpanat; The usual recommended dose of Velakast  is, one tablet should be administered orally as a single dose. Velakast  tablet consist of 100mg of Velpatasvir & 400mg of Sofosbuvir

Sofosbuvir is a NS5B protein inhibitor, protein is essential for viral production. Sofosbuvir is a prodrug form, which get converted into active uridine triphosphate form which is required for anti-viral activity. This dynamic active moiety is get inserted into HCV RNA with the help of NS5B polymerase and leads as chain eliminator. Velpatasvir is pharmacologically acts as NS5A inhibitor; this protein is required for HCV viral production. Velpatasvir is involved its action in viral production process.
VELAKAST UNFAVORABLE EFFECTS 

Serious bradycardia occurs due to concomitant use of Velakast with amiodarone. Insomnia Irritability Headache Fatigue Nausea Asthenia

LAB ABNORMALITIES

Lipase elevation Elevation of creatine kinase Elevation of bilirubin levels

POST MARKETING EFFECTS

Cardiac disorders Rashes Angioedema

The primary sign of Sovihep D is; This mix tablets are utilized to treat the constant hepatitis C viral disease caused by genotype I or III The significant restriction happened while utilizing Hepcinat Plus tablets are lessening of steady virological reaction rate in hepatitis C genotype I or III contaminated patients.

The activity of Sovihep D tablets are occurred by involving in some mechanism;

Sofosbuvir containing sofosbuvir has hostile to hepaciviral movement, which is specifically acting medication displays its activity by disallowing NS5B RNA dependent RNA polymerase protein; fundamental for hepatitis viral duplication. Sofosbuvir is processed to frame uridine triphosphate, a fundamental dynamic metabolite which uncovered a hostile to viral action. The mixture of this dynamic metabolite into hepatitis viral RNA with the assistance of NS5B polymerase and causes viral chain cessation

Daclatasvir containing Daclatasvir removes hostile to viral action by restricting NS5A protein which is needful in viral generation and virion collection

The primary sign of Sofokast-Plus  is; This mix tablets are utilized to treat the constant hepatitis C viral disease caused by genotype I or III The significant restriction happened while utilizing Sofokast-Plus  tablets are lessening of steady virological reaction rate in hepatitis C genotype I or III contaminated patients.

The activity of Sofokast-Plus  tablets are occurred by involving in some mechanism;

Sofosbuvir containing sofosbuvir has hostile to hepaciviral movement, which is specifically acting medication displays its activity by disallowing NS5B RNA dependent RNA polymerase protein; fundamental for hepatitis viral duplication. Sofosbuvir is processed to frame uridine triphosphate, a fundamental dynamic metabolite which uncovered a hostile to viral action. The mixture of this dynamic metabolite into hepatitis viral RNA with the assistance of NS5B polymerase and causes viral chain cessation

Daclatasvir containing Daclatasvir removes hostile to viral action by restricting NS5A protein which is needful in viral generation and virion collection
SOFOKAST - PLUS SIDE EFFECTS 

Side effects occurred in Sofokast-Plus tablet receiving patients such as; Fatigue Headache Insomnia Nausea Pruritus Asthenia Anemia Loss of appetite Flu like syndrome Pyrexia Diarrhea Rash Neutropenia Myalgia Irritability Pancytopenia Increase of creatine kinase, bilirubin, lipase, AST & ALT HBV reoccurrence may occurs Serious bradycardia while combining with amiodarone

We are manfacturer,trader & supplier of Hepcinat Plus Tablets.Hepcinat Plus tablets are hostile to viral medicine Hepcinat Plus tablets are single measurements treatment, it is a doctor prescribed medication utilized by the patients just under the information of restorative expert who are all around rehearsed Daclatasvir isn''''''''''''''''t utilized alone, for better activity it ought to be joined with Sofosbuvir tablet. In some condition Hepcinat Plus is joined with ribavirin, a hostile to viral pharmaceutical utilized as a part of decompensated (Child Pugh B or C) cirrhosis

The primary sign of Hepcinat Plus is; This mix tablets are utilized to treat the constant hepatitis C viral disease caused by genotype I or III The significant restriction happened while utilizing Hepcinat Plus tablets are lessening of steady virological reaction rate in hepatitis C genotype I or III contaminated patients.

The activity of Hepcinat Plus tablets are occurred by involving in some mechanism;

Sofosbuvir containing sofosbuvir has hostile to hepaciviral movement, which is specifically acting medication displays its activity by disallowing NS5B RNA dependent RNA polymerase protein; fundamental for hepatitis viral duplication. Sofosbuvir is processed to frame uridine triphosphate, a fundamental dynamic metabolite which uncovered a hostile to viral action. The mixture of this dynamic metabolite into hepatitis viral RNA with the assistance of NS5B polymerase and causes viral chain cessation

Daclatasvir containing Daclatasvir removes hostile to viral action by restricting NS5A protein which is needful in viral generation and virion collection

Hepcinat Plus tablets are given with or without food, in the condition of chronic hepatitis C viral infection originated by genotype I or III Hepcinat Plus is single dose therapy

Daclatasvir normally is not used alone treatment, it is combined with Sofosbuvir The suggested dosage of Hepcinat Plus is one tablet should be taken as a single dose If Sofosbuvir is discontinued, Daclatasvir also get stopped Genotype I Patient suffered without cirrhosis or with compensated cirrhosis: The recommended usual dosage of Hepcinat Plus is one tablet should be taken as a single dose with or without food In decompensated cirrhosis patients: Hepcinat Plus should be altogether with ribavirin as a single dose

Patient suffered without cirrhosis or with compensated cirrhosis: The recommended usual dosage of Hepcinat Plus is one tablet should be administered as a single dose with or without food In decompensated cirrhosis patients: Hepcinat Plus should be concomitant with ribavirin as a once a day The dosage of ribavirin; The hemoglobin level of patients, dose can be calculated on basis of body weight. Below 75kg: The dosage is 1000mg of ribavirin; suggested for genotype I or III 600mg of ribavirin as an primary dose and followed as 1000mg/per Slightly 75 kg: The dose of 1200mg of ribavirin administrated In decompensated cirrhosis given as twice daily. 

SIDE EFFECTS

Side effects occurred in Hepcinat Plus tablet receiving patients such as; Fatigue Headache Insomnia Nausea Pruritus Asthenia Anemia Loss of appetite Flu like syndrome Pyrexia Diarrhea Rash Neutropenia Myalgia Irritability Pancytopenia Increase of creatine kinase, bilirubin, lipase, AST & ALT HBV reoccurrence may occurs Serious bradycardia while combining with amiodarone

 Hepcinat Plus is manufactured by Natco Pharma Ltd